Gavin L Woodhall

2024

Peripherally-derived LGI1-reactive monoclonal antibodies cause epileptic seizures in vivo

Upadhya, M., Kirmann, T., Wilson, M. A., Simon, C. M., Dhangar, D., Geis, C., Williams, R., Woodhall, G., Hallermann, S., Irani, S. R. & Wright, S. K., 1 Aug 2024, In: Brain. 147, 8, p. 2636-2642 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2023

Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity

Rosenberg, E. C., Chamberland, S., Bazelot, M., Nebet, E. R., Wang, X., McKenzie, S., Jain, S., Greenhill, S., Wilson, M., Marley, N., Salah, A., Bailey, S., Patra, P. H., Rose, R., Chenouard, N., Sun, S. D., Jones, D., Buzsáki, G., Devinsky, O. & Woodhall, G. & 3 others, Scharfman, H. E., Whalley, B. J. & Tsien, R. W., 19 Apr 2023, In: Neuron. 111, 8, p. 1282-1300.e8 28 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2022

Cannabidiol targets a modulatory system for excitatory-inhibitory synaptic coordination, contributing to its anti-seizure action

Rosenberg, E., Chamberland, S., Bazelot, M., Nebet, E. R., Wang, X., McKenzie, S., Jain, S., Greenhill, S., Wilson, M., Salah, A., Bailey, S., Patra, P. H., Rose, R., Chenouard, N., Sun, S. D., Jones, D., Buzsáki, G., Devinsky, O., Woodhall, G. & Scharfman, H. & 2 others, Whalley, B. & Tsien, R., 28 Sept 2022, 68 p.

Research output: Preprint or Working paper › Preprint

2021

Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures

Kreye, J., Wright, S. K., van Casteren, A., Stöffler, L., Machule, M.-L., Reincke, S. M., Nikolaus, M., van Hoof, S., Sanchez-Sendin, E., Homeyer, M. A., Cordero Gómez, C., Kornau, H.-C., Schmitz, D., Kaindl, A. M., Boehm-Sturm, P., Mueller, S., Wilson, M. A., Upadhya, M. A., Dhangar, D. R. & Greenhill, S. & 9 others, Woodhall, G., Turko, P., Vida, I., Garner, C. C., Wickel, J., Geis, C., Fukata, Y., Fukata, M. & Prüss, H., 21 Sept 2021, In: Journal of Experimental Medicine . 218, 11, e20210012.

Research output: Contribution to journal › Article › peer-review

Open Access

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Kainate and AMPA receptors in epilepsy: Cell biology, signalling pathways and possible crosstalk

Henley, J. M., Nair, J. D., Seager, R., Yucel, B. P., Woodhall, G., Henley, B. S., Talandyte, K., Needs, H. I. & Wilkinson, K. A., 1 Sept 2021, In: Neuropharmacology. 195, 108569.

Research output: Contribution to journal › Review article › peer-review

Open Access

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Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis

Wright, S. K., Rosch, R. E., Wilson, M. A., Upadhya, M. A., Dhangar, D. R., Clarke-Bland, C., Wahid, T. T., Barman, S., Goebels, N., Kreye, J., Prüss, H., Jacobson, L., Bassett, D. S., Vincent, A., Greenhill, S. D. & Woodhall, G. L., 20 Sept 2021, In: Communications Biology. 4, 1, 1106.

Research output: Contribution to journal › Article › peer-review

Open Access

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The AMPA receptor antagonist perampanel suppresses epileptic activity in human focal cortical dysplasia

Brito Da Silva, A., Pennifold, J., Henley, B., Chatterjee, K., Bateman, D., Whittaker, R. W., Joshi, A., Kumar, H., Nicholson, C., Baker, M. R., Greenhill, S. D., Walsh, R., Seri, S., Jones, R. S. G., Woodhall, G. L. & Cunningham, M. O., 15 Oct 2021, (E-pub ahead of print) In: Epilepsia Open.

Research output: Contribution to journal › Article › peer-review

Open Access

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2020

Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition

Wright, S. K., Wilson, M. A., Walsh, R., Lo, W. B., Mundil, N., Agrawal, S., Philip, S., Seri, S., Greenhill, S. D. & Woodhall, G. L., 1 Jun 2020, In: Annals of Clinical and Translational Neurology. 7, 6, p. 883-890 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Evaluation of the effect of Cooled HaEmodialysis on Cognitive function in patients suffering with end-stage KidnEy Disease (E-CHECKED): feasibility randomised control trial protocol

Dasgupta, I., Odudu, A., Baharani, J., Fergusson, N., Griffiths, H., Harrison, J., Maruff, P., Thomas, G. N., Woodhall, G., Youseff, S. & Tadros, G., 30 Sept 2020, In: Trials. 21, 1, 820.

Research output: Contribution to journal › Article › peer-review

Open Access

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In vitro characterisation and neurosteroid treatment of an N-Methyl-D-Aspartate receptor antibody-mediated seizure model

Wright, S. K., Rosch, R. E., Wilson, M. A., Upadhya, M. A., Dhangar, D. R., Clarke-Bland, C., Wahid, T. T., Barman, S., Goebels, N., Kreye, J., Prüss, H., Jacobson, L., Bassett, D. S., Vincent, A., Greenhill, S. D. & Woodhall, G. L., 22 Dec 2020.

Research output: Preprint or Working paper › Preprint

Open Access

2019

Bradykinesia is driven by cumulative beta power during continuous movement and alleviated by GABAergic modulation in Parkinson’s disease

Prokic, E., Woodhall, G. L., Williams, A. C., Stanford, I. & Hall, S., 20 Dec 2019, In: Frontiers in Neurology. 10, 1298.

Research output: Contribution to journal › Article › peer-review

Open Access

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Changes in excitatory and inhibitory receptor expression and network activity during induction and establishment of epilepsy in the rat Reduced Intensity Status Epilepticus (RISE) model

Needs, H. I., Henley, B. S., Cavallo, D., Gurung, S., Modebadze, T., Woodhall, G. & Henley, J. M., 1 Nov 2019, In: Neuropharmacology. 158, 107728.

Research output: Contribution to journal › Article › peer-review

Open Access

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2017

Dopamine acting at D1-like, D2-like and α1-adrenergic receptors differentially modulates theta and gamma oscillatory activity in primary motor cortex

Özkan, M., Johnson, N. W., Sehirli, U. S., Woodhall, G. L. & Stanford, I. M., 21 Jul 2017, In: PLoS ONE. 12, 7, 15 p., e0181633.

Research output: Contribution to journal › Article › peer-review

Open Access

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Phase-amplitude coupled persistent theta and gamma oscillations in rat primary motor cortex in vitro

Johnson, N. W., Özkan, M., Burgess, A. P., Prokic, E. J., Wafford, K. A., O'Neill, M. J., Greenhill, S. D., Stanford, I. M. & Woodhall, G. L., Jun 2017, In: Neuropharmacology. 119, p. 141–156 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2016

A low mortality, high morbidity Reduced Intensity Status Epilepticus (RISE) model of epilepsy and epileptogenesis in the rat

Modebadze, T., Morgan, N. H., Pérès, I. A. A., Hadid, R. D., Amada, N., Hill, C., Williams, C., Stanford, I. M., Morris, C. M., Jones, R. S. G., Whalley, B. J. & Woodhall, G. L., 24 Feb 2016, In: PLoS ONE. 11, 2, 19 p., e0147265.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Human brain slices for epilepsy research: pitfalls, solutions and future challenges

Jones, R. S. G., Brito da Silva, A., Whittaker, R. G., Woodhall, G. L. & Cunningham, M. O., 15 Feb 2016, In: Journal of Neuroscience Methods. 260, p. 221-232 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2015

Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons

Prokic, E. J., Weston, C., Yamawaki, N., Hall, S. D., Jones, R. S. G., Stanford, I. M., Ladds, G. & Woodhall, G. L., Aug 2015, In: Neuropharmacology. 95, p. 192–205 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2014

Astroglial d-serine is the endogenous co-agonist at the presynaptic NMDA receptor in rat entorhinal cortex

Lench, A. M., Massey, P. V., Pollegioni, L., Woodhall, G. L. & Jones, R. S. G., Aug 2014, In: Neuropharmacology. 83, p. 118-127 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Background synaptic activity in rat entorhinal cortex shows a progressively greater dominance of inhibition over excitation from deep to superficial layers

Greenhill, S. D., Chamberlain, S. E. L., Lench, A., Massey, P. V., Yuill, K. H., Woodhall, G. L. & Jones, R. S. G., 15 Jan 2014, In: PLoS ONE. 9, 1, 16 p., e85125.

Research output: Contribution to journal › Article › peer-review

Open Access

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GABA-mediated changes in inter-hemispheric beta frequency activity in early-stage Parkinson's disease

Hall, S. D., Prokic, E. J., McAllister, C. J., Rönnqvist, K. C., Williams, A. C., Yamawaki, N., Witton, C., Woodhall, G. L. & Stanford, I. M., 5 Dec 2014, In: Neuroscience. 281, p. 68-76 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Spike firing and IPSPs in layer V pyramidal neurons during beta oscillations in rat primary motor cortex (M1) in vitro

Lacey, M. G., Gooding-Williams, G., Prokic, E. J., Yamawaki, N., Hall, S. D., Stanford, I. M. & Woodhall, G. L., 20 Jan 2014, In: PLoS ONE. 9, 1, 10 p., e85109.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2013

A multimodal perspective on the composition of cortical oscillations: frontiers in human neuroscience

Rönnqvist, K. C., McAllister, C. J., Woodhall, G. L., Stanford, I. M. & Hall, S. D., 25 Mar 2013, In: Frontiers in Human Neuroscience. 7, 132, 9 p., 132.

Research output: Contribution to journal › Article › peer-review

Open Access

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Oscillatory beta activity mediates neuroplastic effects of motor cortex stimulation in humans

McAllister, C. J., Rönnqvist, K. C., Stanford, I. M., Woodhall, G. L., Furlong, P. L. & Hall, S. D., 1 May 2013, In: Journal of Neuroscience. 33, 18, p. 7919-7927 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Reducing suffering in animal models and procedures involving seizures, convulsions and epilepsy

Wolfensohn, S., Hawkins, P., Lilley, E., Anthony, D., Chambers, C., Lane, S., Lawton, M., Robinson, S., Voipio, H.-M. & Woodhall, G., Jan 2013, In: Journal of Pharmacological and Toxicological Methods. 67, 1, p. 9-15 7 p.

Research output: Contribution to journal › Article › peer-review

Reducing suffering in experimental autoimmune encephalomyelitis (EAE)

Wolfensohn, S., Hawkins, P., Lilley, E., Anthony, D., Chambers, C., Lane, S., Lawton, M., Voipio, H.-M. & Woodhall, G., May 2013, In: Journal of Pharmacological and Toxicological Methods. 67, 3, p. 169-176 8 p.

Research output: Contribution to journal › Article › peer-review

2012

Ethosuximide modifies network excitability in the rat entorhinal cortex via an increase in GABA release

Greenhill, S. D., Massey, P., Morgan, N., Woodhall, G. & Jones, R. S. G., Feb 2012, In: Neuropharmacology. 62, 2, p. 807-814 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Frequency selectivity and dopamine-dependence of plasticity at glutamatergic synapses in the subthalamic nucleus

Yamawaki, N., Magill, P. J., Hall, S., Woodhall, G. & Stanford, I., 17 Feb 2012, In: Neuroscience. 203, p. 1-11 11 p., 22209920.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Report of the 2011 RSPCA/UFAW rodent welfare group meeting: harms and benefits of new technologies

Hawkins, P., Burn, C., Deacon, R., Dennison, N., Heath, M., Mackin, P., Tremoleda, J., Webb, A., Woodhall, G., Jennings, M. & Hubrecht, R., Aug 2012, In: Animal Technology and Welfare. 11, 2

Research output: Contribution to journal › Article › peer-review

2011

The role of GABAergic modulation in motor function related neuronal network activity

Hall, S. D., Stanford, I. M., Yamawaki, N., McAllister, C., Rönnqvist, K. C., Woodhall, G. L. & Furlong, P. L., 1 Jun 2011, In: Neuroimage. 56, 3, p. 1506-1510 5 p.

Research output: Contribution to journal › Article › peer-review

File

2010

GABA(A) alpha-1 subunit mediated desynchronization of elevated low frequency oscillations alleviates specific dysfunction in stroke: a case report

Hall, S., Yamawaki, N., Fisher, A., Clauss, R., Woodhall, G. & Stanford, I., 12 Apr 2010, In: Clinical Neurophysiology . 121, 4, p. 549-555 6 p., 20097125.

Research output: Contribution to journal › Article › peer-review

2009

Functional CB2 type cannabinoid receptors at CNS synapses

Morgan, N., Stanford, I. & Woodhall, G., Sept 2009, In: Neuropharmacology. 57, 4, p. 356-368 13 p.

Research output: Contribution to journal › Article › peer-review

2008

Depolarisation and suppression of burst firing activity in the mouse subthalamic nucleus by dopamine D1/D5 receptor activation of a cyclic-nucleotide gated non-specific cation conductance

Loucif, A. J. C., Woodhall, G. L., Sehirli, U. S. & Stanford, I. M., Jul 2008, In: Neuropharmacology. 55, 1, p. 94-105 12 p.

Research output: Contribution to journal › Article › peer-review

Functional characterization of GABAergic pallidopallidal and striatopallidal synapses in the rat globus pallidus in vitro

Sims, R. E., Woodhall, G. L., Wilson, C. L. & Stanford, I. M., Dec 2008, In: European Journal of Neuroscience. 28, 12, p. 2401-2408 8 p.

Research output: Contribution to journal › Article › peer-review

Mobility of NMDA autoreceptors but not postsynaptic receptors at glutamate synapses in the rat entorhinal cortex

Yang, J., Chamberlain, S. E. L., Woodhall, G. L. & Jones, R. S. G., 15 Oct 2008, In: Journal of Physiology. 586, 20, p. 4905-4924 20 p.

Research output: Contribution to journal › Article

File

Modulation of network oscillatory activity and GABAergic synaptic transmission by CB1 cannabinoid receptors in the rat medial entorhinal cortex

Morgan, N., Stanford, I. & Woodhall, G., 19 Jun 2008, In: Neural Plasticity. 2008, 12 p., 808564.

Research output: Contribution to journal › Article › peer-review

Open Access

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Pharmacologically induced and stimulus evoked rhythmic neuronal oscillatory activity in the primary motor cortex in vitro

Yamawaki, N., Stanford, I. M., Hall, S. D. & Woodhall, G. L., 24 Jan 2008, In: Neuroscience. 151, 2, p. 386-395 10 p.

Research output: Contribution to journal › Article › peer-review

2007

Depression of glutamate and GABA release by presynaptic GABA_B receptors in the entorhinal cortex in normal and chronically epileptic rats

Thompson, S. E., Ayman, G., Woodhall, G. L. & Jones, R. S. G., Jun 2007, In: NeuroSignals. 15, 4, p. 202-215 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Differential control of two forms of glutamate release by group III metabotropic glutamate receptors at rat entorhinal synapses

Woodhall, G. L., Ayman, G. & Jones, R. S. G., 10 Aug 2007, In: Neuroscience. 148, 1, p. 7-21 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2006

Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats

Yang, J., Woodhall, G. L. & Jones, R. S. G., 11 Jan 2006, In: Journal of Neuroscience. 26, 2, p. 406-410 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2005

Background synaptic activity in rat entorhinal cortical neurones: differential control of transmitter release by presynaptic receptors

Jones, R. S. G. & Woodhall, G. L., Jan 2005, In: Journal of Physiology. 562, 1, p. 107-120 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Fundamental differences in spontaneous synaptic inhibition between deep and superficial layers of the rat entorhinal cortex

Woodhall, G. L., Bailey, S. J., Thompson, S. E., Evans, D. I. P. & Jones, R. S. G., 18 Apr 2005, In: Hippocampus. 15, 2, p. 232-245 14 p.

Research output: Contribution to journal › Article › peer-review

2004

Dual effects of gabapentin and pregabalin on glutamate release at rat entorhinal synapses in vitro

Cunningham, M. O., Woodhall, G. L., Thompson, S. E., Dooley, D. J. & Jones, R. S. G., 6 Sept 2004, In: European Journal of Neuroscience. 20, 6, p. 1566-1576 11 p.

Research output: Contribution to journal › Article › peer-review

Lamina-specific differences in GABA_B autoreceptor-mediated regulation of spontaneous GABA release in rat entorhinal cortex

Bailey, S. J., Dhillon, A., Woodhall, G. L. & Jones, R. S. G., 1 Jan 2004, In: Neuropharmacology. 46, 1, p. 31-42 12 p.

Research output: Contribution to journal › Article › peer-review

2003

Valproate modifies spontaneous excitation and inhibition at cortical synapses in vitro

Cunningham, M. O., Woodhall, G. L. & Jones, R. S. G., 1 Dec 2003, In: Neuropharmacology. 45, 7, p. 907-917 11 p.

Research output: Contribution to journal › Article › peer-review

2002

Activation of neurokinin-1 receptors promotes GABA release at synapses in the rat entorhinal cortex

Stacey, A. E., Woodhall, G. L. & Jones, R. S. G., 20 Dec 2002, In: Neuroscience. 115, 2, p. 575-586 12 p.

Research output: Contribution to journal › Article › peer-review

Neurokinin-receptor-mediated depolarization of cortical neurons elicits an increase in glutamate release at excitatory synapses

Stacey, A. E., Woodhall, G. L. & Jones, R. S. G., 1 Nov 2002, In: European Journal of Neuroscience. 16, 10, p. 1896-1906 11 p.

Research output: Contribution to journal › Article › peer-review

2001

Activation of presynaptic group III metabotropic glutamate receptors depresses spontaneous inhibition in layer V of the rat entorhinal cortex

Woodhall, G., Evans, D. I. P. & Jones, R. S. G., 16 Jul 2001, In: Neuroscience. 105, 1, p. 71-78 8 p.

Research output: Contribution to journal › Article › peer-review

Gavin L Woodhall

Research output

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