Philip Kitchen

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Philip Kitchen

Dr

 https://sandbox.orcid.org/0000-0002-1558-4673

    • United Kingdom

    Accepting PhD Students

    Personal profile

    Research Interests

    My research interests are focused on the study of membrane proteins, spanning from single molecule studies to advanced tissue engineering. Current projects in the lab include developing iPSC-based models of the human blood-brain barrier, drug discovery for brain oedema by inhibiting aquaporin channel function or localisation, characterising the interactome of various membrane proteins, using mass photometry to characterise membrane protein oligomerisation, optimising solubilisation conditions for G protein-coupled receptors, and cryo-EM studies of aquaporins using novel membrane solubilising agents.

    I have capacity for supervision of undergraduate and Masters level research projects, and am happy to receive expressions of interest for PhD study.

    Biography

    I am a physicist by training (MPhys, University of Warwick). I completed my PhD in the Molecular Organisation and Assembly in Cells doctoral training centre at the University of Warwick, where I developed biophysical tools to study aquaporin water channel proteins. I am currently a BBSRC Discovery fellow based in the School of Biosciences.

    Education/Academic qualification

    PhD, University of Warwick

    1 Sept 2012 → 1 Sept 2016

    Award Date: 1 Sept 2016

    MSc, Mathematical Biology and Biophysical Chemistry, University of Warwick

    1 Sept 2011 → 1 Sept 2012

    Award Date: 1 Sept 2012

    MPhys Physics, University of Warwick

    1 Sept 2007 → 1 Jun 2011

    Award Date: 1 Jul 2011

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    Collaborations and top research areas from the last five years

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    • 27 Article
    • 5 Review article
    • 1 Chapter (peer-reviewed)
    • 1 Letter, comment/opinion or interview

    • Aquaporin-4 and GPRC5B: old and new players in controlling brain oedema

      Passchier, E. M. J., Kerst, S., Brouwers, E., Hamilton, E. M. C., Bisseling, Q., Bugiani, M., Waisfisz, Q., Kitchen, P., Unger, L., Breur, M., Hoogterp, L., de Vries, S. I., Abbink, T. E. M., Kole, M. H. P., Leurs, R., Vischer, H. F., Brignone, M. S., Ambrosini, E., Feillet, F. & Born, A. P. & 4 others, Epstein, L. G., Mansvelder, H. D., Min, R. & van der Knaap, M. S., 1 Aug 2023, In: Brain. 146, 8, p. 3444-3454 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      File

    • Astrocytes in functional recovery following central nervous system injuries

      Alhadidi, Q. M., Bahader, G. A., Arvola, O., Kitchen, P., Shah, Z. A. & Salman, M. M., 13 Sept 2023, (E-pub ahead of print) In: Journal of Physiology.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      File

    • Mechanisms of aquaporin-4 vesicular trafficking in mammalian cells

      Markou, A., Kitchen, P., Aldabbagh, A., Repici, M., Salman, M. M., Bill, R. & Balklava, Z., 16 Dec 2023, (E-pub ahead of print) In: Journal of Neurochemistry.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      File

    • The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

      Alexander, S. P. H., Mathie, A. A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Aldrich, R. W., Attali, B., Baggetta, A. M., Becirovic, E., Biel, M., Bill, R. M., Caceres, A. I., Catterall, W. A., Conner, A. C. & Davies, P. & 53 others, De Clerq, K., Delling, M., Di Virgilio, F., Falzoni, S., Fenske, S., Fortuny-Gomez, A., Fountain, S., George, C., Goldstein, S. A. N., Grimm, C., Grissmer, S., Ha, K., Hammelmann, V., Hanukoglu, I., Hu, M., Ijzerman, A. P., Jabba, S. V., Jarvis, M., Jensen, A. A., Jordt, S. E., Kaczmarek, L. K., Kellenberger, S., Kennedy, C., King, B., Kitchen, P., Liu, Q., Lynch, J. W., Meades, J., Mehlfeld, V., Nicke, A., Offermanns, S., Perez-Reyes, E., Plant, L. D., Rash, L., Ren, D., Salman, M. M., Sieghart, W., Sivilotti, L. G., Smart, T. G., Snutch, T. P., Tian, J., Trimmer, J. S., Van den Eynde, C., Vriens, J., Wei, A. D., Winn, B. T., Wulff, H., Xu, H., Yang, F., Fang, W., Yue, L., Zhang, X. & Zhu, M., 20 Dec 2023, In: British Journal of Pharmacology. 180, Suppl.2, p. S145-S222

      Research output: Contribution to journal › Article › peer-review

      Open Access
      File

    • Assessing water permeability of aquaporins in a proteoliposome-based stopped-flow setup

      Steffen, J. H., Missel, J. W., Al-Jubair, T., Kitchen, P., Salman, M. M., Bill, R. M., Törnroth-Horsefield, S. & Gourdon, P., 17 Jun 2022, In: STAR protocols. 3, 2, 101312.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      File
    View all 34 research outputs