• School of Life & Health Sciences, Aston University, Aston Triangle

      B4 7ET Birmingham

      United Kingdom

    Accepting PhD Students

    Personal profile

    Research Interests

    Since 2010, my research interests have focused upon DNA replication and DNA damage. With my new independent research group at Aston University (established April 2024), my research will now expand into the area of the nuclear membrane - understanding the importance of the connections between DNA replication machinery and the nuclear membrane and how such connections maintain genome stability and prevent ageing-related diseases such as cancer, neurodegeneration and progeroid syndromes.

    I have experience of working with a wide range of techniques for studying the dynamics of DNA replication. Such techniques include immunofluorescence microscopy and chromatin isolation (monitoring the binding and disassembly of replication factors from chromatin), DNA fibres (origin firing, inter-origin distances, replication fork progression, replication fork stalling and replication fork restart), replication foci formation (DNA replication timing throughout S-phase), alkaline gel electrophoresis (lagging strand maturation), affinity chromatography (protein-protein interactions) and cell viability assays.

    I am keen to collaborate, so please get in touch if you are interested.

    Qualifications

    BSc (Hons) Biochemistry, Lancaster University, 2006.

    PhD Biochemistry, University of Sheffield, 2010.

    Associate Fellow of the Higher Education Academy, University of Birmingham, 2018.

    Fellow of the Higher Education Academy, University of Birmingham, 2023.

    Employment

    2024 – date: Lecturer in School of Biosciences, Aston University.

    2016 – 2024: Post doctoral researcher, University of Birmingham with Prof Aga Gambus.

    2010 – 2016: Post doctoral researcher, University of Birmingham with Prof Eva Petermann.

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