2D-3D registration of CT vertebra volume to fluoroscopy projection: a calibration model assessment

P. Bifulco*, M. Cesarelli, R. Allen, M. Romano, A. Fratini, G. Pasquariello

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


This study extends a previous research concerning intervertebral motion registration by means of 2D dynamic fluoroscopy to obtain a more comprehensive 3D description of vertebral kinematics. The problem of estimating the 3D rigid pose of a CT volume of a vertebra from its 2D X-ray fluoroscopy projection is addressed. 2D-3D registration is obtained maximising a measure of similarity between Digitally Reconstructed Radiographs (obtained from the CT volume) and real fluoroscopic projection. X-ray energy correction was performed. To assess the method a calibration model was realised a sheep dry vertebra was rigidly fixed to a frame of reference including metallic markers. Accurate measurement of 3D orientation was obtained via single-camera calibration of the markers and held as true 3D vertebra position; then, vertebra 3D pose was estimated and results compared. Error analysis revealed accuracy of the order of 0.1 degree for the rotation angles of about 1mm for displacements parallel to the fluoroscopic plane, and of order of 10mm for the orthogonal displacement.

Original languageEnglish
Number of pages8
JournalEURASIP Journal on Advances in Signal Processing
Publication statusPublished - 30 Jun 2010

Bibliographical note

© 2010 The Author(s). This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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