A novel chronotherapeutic system for the treatment of primary open-angle glaucoma

Doina Gherghel (Inventor), Barbara Conway (Inventor)

Research output: Patent

Abstract

Chronotherapeutic delivery system for treating primary open-angle glaucoma, comprising a delivery system incorporating pharmaceutical products for delivery to an eye in the treatment of primary open-angle glaucoma (POAG), comprising: (a) a biocompatible erodible material incorporating a therapeutically-effective amount of a prostaglandin analogue, and (b) a reservoir containing a therapeutically-effective amount of a beta-blocker, whereby, when the delivery system is placed in the eye the prostaglandin analogue is delivered gradually as the erodible material is eroded, and the beta-blocker is delivered rapidly when at least a predetermined portion of the erodible material has been eroded.
Original languageEnglish
Patent numberP715802EP/1196/ US 2009/0155338 A1
Publication statusPublished - 18 Jun 2009

Keywords

  • glaucoma
  • chronotherapy

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