TY - JOUR
T1 - Additive manufacturing of anti-SARS-CoV-2 Copper-Tungsten-Silver alloy
AU - Robinson, John
AU - Arjunan, Arun
AU - Baroutaji, Ahmad
AU - Martí, Miguel
AU - Tuñón Molina, Alberto
AU - Serrano-Aroca, Ángel
AU - Pollard, Andrew
PY - 2021/11/18
Y1 - 2021/11/18
N2 - Purpose: The COVID-19 pandemic emphasises the need for antiviral materials that can reduce airborne and surface-based virus transmission. This study aims to propose the use of additive manufacturing (AM) and surrogate modelling for the rapid development and deployment of novel copper-tungsten-silver (Cu-W-Ag) microporous architecture that shows strong antiviral behaviour against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Design/methodology/approach: The research combines selective laser melting (SLM), in-situ alloying and surrogate modelling to conceive the antiviral Cu-W-Ag architecture. The approach is shown to be suitable for redistributed manufacturing by representing the pore morphology through a surrogate model that parametrically manipulates the SLM process parameters: hatch distance (h_d), scan speed (S_s) and laser power (L_p). The method drastically simplifies the three-dimensional (3D) printing of microporous materials by requiring only global geometrical dimensions solving current bottlenecks associated with high computed aided design data transfer required for the AM of porous materials. Findings: The surrogate model developed in this study achieved an optimum parametric combination that resulted in microporous Cu-W-Ag with average pore sizes of 80 µm. Subsequent antiviral evaluation of the optimum architecture showed 100% viral inactivation within 5 h against a biosafe enveloped ribonucleic acid viral model of SARS-CoV-2. Research limitations/implications: The Cu-W-Ag architecture is suitable for redistributed manufacturing and can help reduce surface contamination of SARS-CoV-2. Nevertheless, further optimisation may improve the virus inactivation time. Practical implications: The study was extended to demonstrate an open-source 3D printed Cu-W-Ag antiviral mask filter prototype. Social implications: The evolving nature of the COVID-19 pandemic brings new and unpredictable challenges where redistributed manufacturing of 3D printed antiviral materials can achieve rapid solutions. Originality/value: The papers present for the first time a methodology to digitally conceive and print-on-demand a novel Cu-W-Ag alloy that shows high antiviral behaviour against SARS-CoV-2.
AB - Purpose: The COVID-19 pandemic emphasises the need for antiviral materials that can reduce airborne and surface-based virus transmission. This study aims to propose the use of additive manufacturing (AM) and surrogate modelling for the rapid development and deployment of novel copper-tungsten-silver (Cu-W-Ag) microporous architecture that shows strong antiviral behaviour against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Design/methodology/approach: The research combines selective laser melting (SLM), in-situ alloying and surrogate modelling to conceive the antiviral Cu-W-Ag architecture. The approach is shown to be suitable for redistributed manufacturing by representing the pore morphology through a surrogate model that parametrically manipulates the SLM process parameters: hatch distance (h_d), scan speed (S_s) and laser power (L_p). The method drastically simplifies the three-dimensional (3D) printing of microporous materials by requiring only global geometrical dimensions solving current bottlenecks associated with high computed aided design data transfer required for the AM of porous materials. Findings: The surrogate model developed in this study achieved an optimum parametric combination that resulted in microporous Cu-W-Ag with average pore sizes of 80 µm. Subsequent antiviral evaluation of the optimum architecture showed 100% viral inactivation within 5 h against a biosafe enveloped ribonucleic acid viral model of SARS-CoV-2. Research limitations/implications: The Cu-W-Ag architecture is suitable for redistributed manufacturing and can help reduce surface contamination of SARS-CoV-2. Nevertheless, further optimisation may improve the virus inactivation time. Practical implications: The study was extended to demonstrate an open-source 3D printed Cu-W-Ag antiviral mask filter prototype. Social implications: The evolving nature of the COVID-19 pandemic brings new and unpredictable challenges where redistributed manufacturing of 3D printed antiviral materials can achieve rapid solutions. Originality/value: The papers present for the first time a methodology to digitally conceive and print-on-demand a novel Cu-W-Ag alloy that shows high antiviral behaviour against SARS-CoV-2.
KW - 3D printing
KW - Additive manufacturing
KW - Antiviral
KW - Copper
KW - COVID-19
KW - SARS-CoV-2
KW - Selective laser melting
KW - Silver
KW - Tungsten
UR - https://www.emerald.com/insight/content/doi/10.1108/RPJ-06-2021-0131/full/pdf
UR - http://www.scopus.com/inward/record.url?scp=85113804146&partnerID=8YFLogxK
U2 - 10.1108/RPJ-06-2021-0131
DO - 10.1108/RPJ-06-2021-0131
M3 - Article
AN - SCOPUS:85113804146
SN - 1355-2546
VL - 27
SP - 1831
EP - 1849
JO - Rapid Prototyping Journal
JF - Rapid Prototyping Journal
IS - 10
ER -