Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition

Igor O. Kozlov*, Evgeny A. Zherebtsov, Mikhail A. Mezentsev, Valery V. Shupletsov, Elena V. Potapova, Angelina I. Zherebtsova, Viktor V. Dremin, Andrey V. Dunaev, Igor V. Meglinski

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


Presently, in the modern laser Doppler flowmetry (LDF) the distribution of blood perfusion and its changes along the Doppler shift frequencies are simply ignored and/or not properly addressed. Utilizing the registered power spectrum of photocurrent, we introduce an LDF signal processing approach suitable for expanding of diagnostic capabilities of the technique. In particular, we demonstrate that it is possible to determine how the oscillations of blood flow (cardiac, breathe, myogenic, etc.) are distributed along the Doppler shift frequency. Wavelet analysis is utilized to extract the oscillations corresponded to the particular frequency sub-bands of blood perfusion. The main purpose of this study is to identify influence of local pressure by fiber optic probe on cardiac oscillations and their distribution along frequency of Doppler shift.

Original languageEnglish
Article number110791Q
JournalProceedings of SPIE - International Society for Optical Engineering
Publication statusPublished - 22 Jul 2019
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: 23 Jun 201925 Jun 2019

Bibliographical note

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  • Blood flow oscillations
  • Blood perfusion
  • Laser Doppler flowmetry
  • Probe pressure effects
  • Spectrum decomposition


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