Abstract
Objective: To review the literature regarding the use of fish oils in the treatment of psychiatric illness.
Method: A Medline search was conducted in September 1999.
Results: Five papers have investigated omega-3 fatty acids levels in depression. One study used omega-3 fatty acids as an adjunctive therapy in bipolar disorder. Four studies used fatty acids as an adjunctive therapy in schizophrenia.
Conclusion: There is a great deal of current research in this field. While omega-3 fatty acids levels may be lowered in depression, there are no data suggesting that omega-3 fatty acids are effective. One paper indicates that omega-3 fatty acids are effective in bipolar disorders. The data on schizophrenia are conflicting. Omega-3 and omega-6 fatty acids have proved effective. Most of the evidence suggests that the main effect is an improvement in negative symptoms. One recent study showed that omega-3 fatty acids had no effect on negative symptoms.
Method: A Medline search was conducted in September 1999.
Results: Five papers have investigated omega-3 fatty acids levels in depression. One study used omega-3 fatty acids as an adjunctive therapy in bipolar disorder. Four studies used fatty acids as an adjunctive therapy in schizophrenia.
Conclusion: There is a great deal of current research in this field. While omega-3 fatty acids levels may be lowered in depression, there are no data suggesting that omega-3 fatty acids are effective. One paper indicates that omega-3 fatty acids are effective in bipolar disorders. The data on schizophrenia are conflicting. Omega-3 and omega-6 fatty acids have proved effective. Most of the evidence suggests that the main effect is an improvement in negative symptoms. One recent study showed that omega-3 fatty acids had no effect on negative symptoms.
Original language | English |
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Pages (from-to) | 3-11 |
Number of pages | 9 |
Journal | Acta Psychiatrica Scandinavica |
Volume | 102 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jul 2000 |
Keywords
- Bipolar Disorder
- Depression
- Fatty Acids, Omega-3
- Fish Oils
- Humans
- Mental Disorders
- Schizophrenia
- Treatment Outcome