Characterization and modelling the mechanical behaviour of poly (l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding

Huidong Wei; Shiyong Yan; Saurav Geol; Gary Menary

doi:10.1007/s12289-018-01463-2

Characterization and modelling the mechanical behaviour of poly (l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding

Huidong Wei, Shiyong Yan, Saurav Geol, Gary Menary^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

Original language	English
Pages (from-to)	43-57
Number of pages	15
Journal	International Journal of Material Forming
Volume	13
Early online date	10 Jan 2019
DOIs	https://doi.org/10.1007/s12289-018-01463-2
Publication status	Published - 1 Jan 2020

Bibliographical note

Copyright The Author(s) 2019. Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Funding: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 691238 involving Italian National Agency for New Technologies, Energy and Sustainable Economic Development (Italy), University of Warwick (UK), Queen’s University Belfast (UK) and California Institute of Technology (US).

Keywords

Mechanical behaviour
Constitutive model
Stretch blow moulding
Glass transition
PLLA

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10.1007/s12289-018-01463-2Licence: CC BY 3.0

Characterization and modelling the mechanical behaviour of poly(l-lactic acid)
Copyright The Author(s) 2019. Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Final published version, 2.33 MBLicence: CC BY 3.0

Cite this

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title = "Characterization and modelling the mechanical behaviour of poly (l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding",

abstract = "Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.",

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N1 - Copyright The Author(s) 2019. Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Funding: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 691238 involving Italian National Agency for New Technologies, Energy and Sustainable Economic Development (Italy), University of Warwick (UK), Queen’s University Belfast (UK) and California Institute of Technology (US).

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N2 - Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

AB - Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

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JO - International Journal of Material Forming

JF - International Journal of Material Forming

ER -

Characterization and modelling the mechanical behaviour of poly (l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding

Abstract

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Keywords

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