Clinical guidelines on long-term pharmacotherapy for bipolar disorder in children and adolescents

Joanna H. Cox, Stefano Seri, Andrea E. Cavanna

Research output: Contribution to journalReview articlepeer-review


Bipolar disorder is a severe affective disorder which can present in adolescence, or sometimes earlier, and often requires a pharmacotherapeutic approach. The phenomenology of bipolar disorder in children and adolescents appears to differ from that of adult patients, prompting the need for specific pharmacotherapy guidelines for long-term management in this patient population. Current treatment guidelines were mainly developed based on evidence from studies in adult patients, highlighting the requirement for further research into the pharmacotherapy of children and adolescents with bipolar disorder. This review compares and critically analyzes the available guidelines, discussing the recommended medication classes, their mechanisms of action, side effect profiles and evidence base
Original languageEnglish
Pages (from-to)135-143
Number of pages9
JournalJournal of Clinical Sleep Medicine
Issue number1
Publication statusPublished - 21 Jan 2014

Bibliographical note

© 2014 by the authors; licensee MDPI, Basel, Switzerland.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


  • adolescents
  • bipolar disorder
  • children
  • guidelines
  • pharmacotherapy


Dive into the research topics of 'Clinical guidelines on long-term pharmacotherapy for bipolar disorder in children and adolescents'. Together they form a unique fingerprint.

Cite this