Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes

Keyphrases

• Epitope 100%
• HLA-A*0201 100%
• In Vivo Analysis 100%
• Bioinformatics Methods 100%
• Anchorless 100%
• Peptide-MHC Binding 100%
• In Silico 100%
• Amino Acids 66%
• MHC Molecules 66%
• Binding Affinity 66%
• Quantitative Structure-affinity Relationship 66%
• Binding Peptide 66%
• High Affinity 33%
• Peptide Binding 33%
• MHC Class I 33%
• Prediction Method 33%
• Predictivity 33%
• HLA-A2 33%
• Anchor Position 33%
• Nonamers 33%
• Vaccine Design 33%
• Epitope Identification 33%
• Class I Alleles 33%
• Bioinformatic Prediction 33%
• Relationship Model 33%
• Peptide Interaction 33%
• Cooperativity 33%
• Multiple Positions 33%
• Immunomodulation 33%
• Component Interaction 33%

Biochemistry, Genetics and Molecular Biology

• HLA-A 100%
• Computer Model 100%
• Binding Affinity 66%
• Amino Acids 66%
• Allele 33%
• MHC Class I 33%
• Immunomodulation 33%
• Cooperation 33%
• Fluorescence Activated Cell Sorting 33%