Direct optical generation of singlet oxygen in the regulation of vascular tone

Irina N. Novikova*, Mikhail V. Volkov, Lyubov V. Eratova, Denis I. Myalitsin, Viktor V. Dremin

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


An approach to visualization of the vascular bed with the possibility of assessing changes in blood filling and identifying diagnostically significant periodic changes in the signal by analyzing speckle images is proposed. The effect of singlet oxygen by direct excitation of an oxygen molecule by 1267 nm laser radiation on changes in the vascular bed parameters was studied using this approach.

Original languageEnglish
Article number121470O
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 19 May 2022
EventTissue Optics and Photonics II 2022 - Virtual, Online
Duration: 9 May 202220 May 2022

Bibliographical note

Copyright 2022 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Funding Information:
The work was supported by the Russian Science Foundation under project No. 21-75-00086 (animal studies) and the grant of the President of the Russian Federation for state support of young Russian scientists No. MK-398.2021.4 (development of a device for generating singlet oxygen).


  • 1267 nm
  • direct optical generation
  • high-resolution speckle imaging
  • PPG
  • singlet oxygen
  • vascular bed


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