Emerging roles for AQP in mammalian extracellular vesicles

Charlotte E. Clarke-Bland; Roslyn M. Bill; Andrew Devitt

doi:10.1016/j.bbamem.2021.183826

Emerging roles for AQP in mammalian extracellular vesicles

Charlotte E. Clarke-Bland, Roslyn M. Bill, Andrew Devitt

Research output: Contribution to journal › Article › peer-review

Abstract

Recent research in the aquaporin (AQP) field has identified a role for diverse AQPs in extracellular vesicles (EV). Though still in its infancy, there is a growing body of knowledge in the area; AQPs in EV have been suggested as biomarkers for disease, as drug targets and show potential as therapeutics. To advance further in this field, AQPs in EV must be better understood. Here we summarize current knowledge of the presence and function of AQPs in EV and hypothesise their roles in health and disease.

Original language	English
Article number	183826
Journal	BBA -Biomembranes
Volume	1864
Issue number	3
Early online date	27 Nov 2021
DOIs	https://doi.org/10.1016/j.bbamem.2021.183826
Publication status	Published - 1 Mar 2022

Bibliographical note

This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0)

Funding: We thank the Biotechnology and Biological Sciences Research Council for their support (through BB/P025927/1 to Roslyn Bill and BB/S00324X/1 to Andrew Devitt).

Keywords

Aquaporin
Exosome
Extracellular vesicle
Inflammation
Microvesicle
Oedema
Signalling
Water channel

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10.1016/j.bbamem.2021.183826Licence: CC BY 3.0

AAM-Emerging roles for AQP in mammalian extracellular vesicles
(c) 2021, The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0
Accepted author manuscript, 5.05 MBLicence: CC BY 3.0

https://linkinghub.elsevier.com/retrieve/pii/S0005273621002741

Cite this

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title = "Emerging roles for AQP in mammalian extracellular vesicles",

abstract = "Recent research in the aquaporin (AQP) field has identified a role for diverse AQPs in extracellular vesicles (EV). Though still in its infancy, there is a growing body of knowledge in the area; AQPs in EV have been suggested as biomarkers for disease, as drug targets and show potential as therapeutics. To advance further in this field, AQPs in EV must be better understood. Here we summarize current knowledge of the presence and function of AQPs in EV and hypothesise their roles in health and disease.",

keywords = "Aquaporin, Exosome, Extracellular vesicle, Inflammation, Microvesicle, Oedema, Signalling, Water channel",

author = "Clarke-Bland, {Charlotte E.} and Bill, {Roslyn M.} and Andrew Devitt",

note = "This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0) Funding: We thank the Biotechnology and Biological Sciences Research Council for their support (through BB/P025927/1 to Roslyn Bill and BB/S00324X/1 to Andrew Devitt).",

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KW - Exosome

KW - Extracellular vesicle

KW - Inflammation

KW - Microvesicle

KW - Oedema

KW - Signalling

KW - Water channel

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Emerging roles for AQP in mammalian extracellular vesicles

Abstract

Bibliographical note

Keywords

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Investigating the Roles of Aquaporin 4 in Intracellular and Extracellular Vesicles in Models of Traumatic Injury

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Emerging roles for AQP in mammalian extracellular vesicles

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Student theses

Investigating the Roles of Aquaporin 4 in Intracellular and Extracellular Vesicles in Models of Traumatic Injury

Cite this