Hyperlocomotion test for assessing behavioral disorders

Dan Ma, Paul C. Guest*

*Corresponding author for this work

Research output: Chapter in Book/Published conference outputChapter


Under- or overfeeding during pregnancy can lead to behavioral deficits in the offspring in later life. Here, we present a protocol for setting up and carrying out the hyperlocomotion test for assessing behavioral symptoms such as psychosis or mania. As an example, we use the acute rat phencyclidine-injection model which exhibits hyperlocomotion and stereotypic behaviors, resembling the positive symptoms of schizophrenia.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
EditorsP. Guest
PublisherHumana Press
Number of pages5
ISBN (Electronic)978-1-4939-7614-0
ISBN (Print)978-1-4939-7613-3
Publication statusPublished - 30 Jan 2018

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Behavioral deficits
  • Hyperlocomotion test
  • Nutritional programming
  • PCP
  • Psychosis


Dive into the research topics of 'Hyperlocomotion test for assessing behavioral disorders'. Together they form a unique fingerprint.

Cite this