TY - JOUR
T1 - DSM-5 Autism Spectrum Disorder
T2 - in search of essential behaviours for diagnosis
AU - Carrington, Sarah J.
AU - Kent, Rachel G.
AU - Maljaars, Jarymke
AU - Le Couteur, Ann
AU - Gould, Judith
AU - Wing, Lorna
AU - Noens, Ilse
AU - van Berckelaer-Onnes, Ina
AU - Leekam, Susan R.
N1 - © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/)
PY - 2014/6/1
Y1 - 2014/6/1
N2 - The objective of this study was to identify a set of 'essential' behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, 'essential' behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.
AB - The objective of this study was to identify a set of 'essential' behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, 'essential' behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.
KW - abbreviaved
KW - autism spectrum disorder
KW - diagnosis
KW - DISCO
KW - DSM-5
UR - http://www.scopus.com/inward/record.url?scp=84898754161&partnerID=8YFLogxK
UR - https://www.sciencedirect.com/science/article/pii/S1750946714000695?via%3Dihub
U2 - 10.1016/j.rasd.2014.03.017
DO - 10.1016/j.rasd.2014.03.017
M3 - Article
AN - SCOPUS:84898754161
SN - 1750-9467
VL - 8
SP - 701
EP - 715
JO - Research in autism spectrum disorders
JF - Research in autism spectrum disorders
IS - 6
ER -