Impact of Bariatric Surgery-Induced Weight Loss on Anterior Eye Health in Patients with Obesity

Said Karimzad, Paramdeep S. Bilkhu, James S. Wolffsohn, Srikanth Bellary, Hala Shokr, Rishi Singhal, Doina Gherghel

Research output: Contribution to journalArticlepeer-review


The aim of the present research was to assess the effect of bariatric surgery-induced weight loss on the tear film and ocular surface of patients with obesity. A total of 29 participants with obesity (aged 47.2 10.1 years, 8 male) were measured at baseline and followed up one year after Roux-en-Y gastric bypass (RYGB) surgery. General anthropometric data, as well as serum lipid markers of cholesterol, were assessed in all individuals. Bilateral anterior eye measurements of tear meniscus height (TMH), non-invasive tear breakup time, bulbar and limbal redness and infrared meibography were captured using the Keratograph K5M (Oculus) and ocular surface damage was evaluated using fluorescein sodium and lissamine green staining. Bariatric surgery resulted in significant loss of weight (body mass index p < 0.001) and an improvement in the blood lipid profile (p < 0.01) in all participants. However, there were no statistically significant differences between the baseline and one-year follow-up for any of the measured clinical ocular surface and tear film variables (all p > 0.05). Although there were trends for a reduced TMH and a decrease in meibomian gland dropout after bariatric surgery, these differences were also insignificant (p > 0.05). In conclusion, weight reduction through bariatric surgery did not have an effect on the tear film or ocular surface in unselected patients with obesity.
Original languageEnglish
Article number2462
Issue number12
Publication statusPublished - 14 Jun 2022

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© 2022 by the authors.
Licensee MDPI, Basel, Switzerland.
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  • bariatric surgery
  • cholesterol
  • lipid
  • obesity
  • ocular surface
  • tear film


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