Innovative 2D nanomaterial integrated fiber optic sensors for biochemical applications

Xianfeng Chen, Miguel V. Andrés, Lin Zhang

Research output: Chapter in Book/Published conference outputConference publication


We report our latest investigations on 2D-layered materials integrated fiber optic configurations for chemical and labelfree biosensing applications. Due to the favorable combination of exceptionally high surface-to-volume ratio and excellent optical and biochemical properties, graphene oxide (GO) and black phosphorus (BP) were deposited on fiber grating device as the bio-photonic linking layer to provide the remarkable platform for light-matter interface and affinity binding interaction. We developed a novel in-situ layer-by-layer (i-LbL) deposition technique based on chemicalbonding associated with physical-adsorption for the deposition of 2D materials. This approach secured high-quality 2D materials deposition on cylindrical fiber with strong adhesion as well as a prospective thickness control. By taking advantage of i-LbL deposition, the unique optical tunable features and polarization-selective characteristics have been experimentally observed. Several 2D material integrated fiber optic sensors have been proposed for chemical and biochemical applications, such as GO-long period grating (GO-LPG) based Hemoglobin sensor, GO dual-peak LPG (GO-dLPG) based label-free immunosensor, and the first BP fiber optic chemical sensor based on BP-tilted fiber grating (BP-TFG). We believe that 2D material integrated fiber optic configurations open the path as highly sensitive biophotonic platform for food safety, environmental monitoring, clinical diagnostics and biomedical applications.

Original languageEnglish
Title of host publicationMicro-Structured and Specialty Optical Fibres V
ISBN (Electronic)9781510618886
Publication statusPublished - 9 May 2018
EventMicro-Structured and Specialty Optical Fibres V 2018 - Strasbourg, France
Duration: 25 Apr 201826 Apr 2018

Publication series

NameProceedings of SPIE
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


ConferenceMicro-Structured and Specialty Optical Fibres V 2018

Bibliographical note

Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.


  • Black phosphorus
  • Fiber grating
  • Graphene oxide
  • Heavy metal
  • Hemoglobin
  • Immunosensor
  • Optical biosensor


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