Interpretation of DNA data within the context of UK forensic science: evaluation

Roberto Puch-solis*, Susan Pope

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Forensic DNA provides a striking contribution to the provision of justice worldwide. It has proven to be crucial in the investigative phase of an unsolved crime where a suspect needs to be identified, e.g. from a DNA database search both nationally and internationally. It is also a powerful tool in the assignment of evidential weight to the comparison of a profile of a person of interest and a crime scene profile. The focus of this document is the evaluation of autosomal profiles for criminal trials in the UK. A separate review covers investigation and evaluation of Y-STR profiles, investigation using autosomal profiles, kinship analysis, body identification and Forensic Genetic Genealogy investigations. In less than 40 years, forensic DNA profiling has developed from a specialist technique to everyday use. Borrowing on advances in genome typing technology, forensic DNA profiling has experienced a substantial increase in its sensitivity and informativeness. Alongside this development, novel interpretation methodologies have also been introduced. This document describes the state of the art and future advances in the interpretation of forensic DNA data.
Original languageEnglish
Pages (from-to)405–413
Number of pages9
JournalEmerging Topics in Life Sciences
Issue number3
Early online date24 May 2021
Publication statusPublished - 24 Sept 2021

Bibliographical note

© 2021 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and the Royal Society of Biology and distributed under the Creative Commons
Attribution License 4.0 (CC BY).


  • DNA data
  • DNA profiling
  • forensic
  • interpretation


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