Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances

Evgeny A. Zherebtsov; Victor V. Dremin; Elena V. Zharkikh; Andrey V. Dunaev; Igor O. Kozlov; Edik U. Rafailov; Angelina I. Zherebtsova; Jürgen Popp; Valery V. Tuchin; Francesco S. Pavone

doi:10.1117/12.2289551

Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances

Evgeny A. Zherebtsov, Victor V. Dremin, Elena V. Zharkikh, Andrey V. Dunaev, Igor O. Kozlov, Edik U. Rafailov, Angelina I. Zherebtsova, Jürgen Popp (Editor), Valery V. Tuchin, Francesco S. Pavone (Editor)

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

Laser Doppler flowmetry (LDF) is widely used to study blood microcirculation in the skin. However, during tradition signal processing based on the integral estimations of the power spectrum of detector photocurrent, the significant part of the information about the skin blood ow is lost. In this study, we propose to analyse the distribution of the blood perfusion over the Doppler shift frequencies, which correlate with the RBC velocity. This approach provides localisation of the blood ow oscillations in different subranges of the Doppler shift. The method applied together with the wavelet analysis has been tested in healthy volunteers and patients with psoriasis on the unaffected surface of the skin. It was revealed, that the significant difference in the amplitude of myogenic oscillations is allocated in the region of the low frequency Doppler shift (1-200 Hz). This frequency region can be associated with the signal from slow components of the skin microcirculation, that can point out on a different state of the lymphatic system of the skin in psoriasis.

Original language	English
Title of host publication	Proceedings of SPIE
Publisher	SPIE
Number of pages	4
Volume	10685
DOIs	https://doi.org/10.1117/12.2289551
Publication status	Published - 17 May 2018
Event	Biophotonics: Photonic Solutions for Better Health Care - Strasbourg, France Duration: 22 Apr 2018 → 26 Apr 2018

Publication series

Name	Proceedings of SPIE
Publisher	SPIE
Volume	10685
ISSN (Print)	0277-786X

Conference

Conference	Biophotonics: Photonic Solutions for Better Health Care
Period	22/04/18 → 26/04/18

Bibliographical note

Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

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10.1117/12.2289551

Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances
Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
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Zherebtsov, E. A., Dremin, V. V., Zharkikh, E. V., Dunaev, A. V., Kozlov, I. O., Rafailov, E. U., Zherebtsova, A. I., Popp, J. (Ed.), Tuchin, V. V., & Pavone, F. S. (Ed.) (2018). Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances. In Proceedings of SPIE (Vol. 10685 ). Article 106854O (Proceedings of SPIE; Vol. 10685 ). SPIE. https://doi.org/10.1117/12.2289551

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title = "Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances",

abstract = "Laser Doppler flowmetry (LDF) is widely used to study blood microcirculation in the skin. However, during tradition signal processing based on the integral estimations of the power spectrum of detector photocurrent, the significant part of the information about the skin blood ow is lost. In this study, we propose to analyse the distribution of the blood perfusion over the Doppler shift frequencies, which correlate with the RBC velocity. This approach provides localisation of the blood ow oscillations in different subranges of the Doppler shift. The method applied together with the wavelet analysis has been tested in healthy volunteers and patients with psoriasis on the unaffected surface of the skin. It was revealed, that the significant difference in the amplitude of myogenic oscillations is allocated in the region of the low frequency Doppler shift (1-200 Hz). This frequency region can be associated with the signal from slow components of the skin microcirculation, that can point out on a different state of the lymphatic system of the skin in psoriasis.",

author = "Zherebtsov, {Evgeny A.} and Dremin, {Victor V.} and Zharkikh, {Elena V.} and Dunaev, {Andrey V.} and Kozlov, {Igor O.} and Rafailov, {Edik U.} and Zherebtsova, {Angelina I.} and J{\"u}rgen Popp and Tuchin, {Valery V.} and Pavone, {Francesco S.}",

note = "Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; Biophotonics: Photonic Solutions for Better Health Care ; Conference date: 22-04-2018 Through 26-04-2018",

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Zherebtsov, EA, Dremin, VV, Zharkikh, EV, Dunaev, AV, Kozlov, IO, Rafailov, EU, Zherebtsova, AI, Popp, J (ed.), Tuchin, VV & Pavone, FS (ed.) 2018, Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances. in Proceedings of SPIE. vol. 10685 , 106854O, Proceedings of SPIE, vol. 10685 , SPIE, Biophotonics: Photonic Solutions for Better Health Care, 22/04/18. https://doi.org/10.1117/12.2289551

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AU - Zherebtsov, Evgeny A.

AU - Dremin, Victor V.

AU - Zharkikh, Elena V.

AU - Dunaev, Andrey V.

AU - Kozlov, Igor O.

AU - Rafailov, Edik U.

AU - Zherebtsova, Angelina I.

AU - Tuchin, Valery V.

A2 - Popp, Jürgen

A2 - Pavone, Francesco S.

N1 - Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2018/5/17

Y1 - 2018/5/17

N2 - Laser Doppler flowmetry (LDF) is widely used to study blood microcirculation in the skin. However, during tradition signal processing based on the integral estimations of the power spectrum of detector photocurrent, the significant part of the information about the skin blood ow is lost. In this study, we propose to analyse the distribution of the blood perfusion over the Doppler shift frequencies, which correlate with the RBC velocity. This approach provides localisation of the blood ow oscillations in different subranges of the Doppler shift. The method applied together with the wavelet analysis has been tested in healthy volunteers and patients with psoriasis on the unaffected surface of the skin. It was revealed, that the significant difference in the amplitude of myogenic oscillations is allocated in the region of the low frequency Doppler shift (1-200 Hz). This frequency region can be associated with the signal from slow components of the skin microcirculation, that can point out on a different state of the lymphatic system of the skin in psoriasis.

AB - Laser Doppler flowmetry (LDF) is widely used to study blood microcirculation in the skin. However, during tradition signal processing based on the integral estimations of the power spectrum of detector photocurrent, the significant part of the information about the skin blood ow is lost. In this study, we propose to analyse the distribution of the blood perfusion over the Doppler shift frequencies, which correlate with the RBC velocity. This approach provides localisation of the blood ow oscillations in different subranges of the Doppler shift. The method applied together with the wavelet analysis has been tested in healthy volunteers and patients with psoriasis on the unaffected surface of the skin. It was revealed, that the significant difference in the amplitude of myogenic oscillations is allocated in the region of the low frequency Doppler shift (1-200 Hz). This frequency region can be associated with the signal from slow components of the skin microcirculation, that can point out on a different state of the lymphatic system of the skin in psoriasis.

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T2 - Biophotonics: Photonic Solutions for Better Health Care

Y2 - 22 April 2018 through 26 April 2018

ER -

Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances

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