Measurement of apoptotic cell clearance in vitro

Andrew Devitt, Christopher D. Gregory

Research output: Chapter in Book/Published conference outputChapter (peer-reviewed)peer-review


The phagocytic clearance of apoptotic cells is a highly efficient and nonphlogistic process in vivo. Research in this area has been limited, at least in part, by technical difficulties associated with the techniques used in the detailed study of apoptotic cell clearance mechanisms. This chapter provides details of methods that may be used to study apoptotic cell clearance in vitro. Such methods have been used successfully to identify phagocyte-associated or apoptotic cell-associated molecular players in the recognition process.
Original languageEnglish
Title of host publicationApoptosis methods and protocols
EditorsHugh J.M. Brady
Place of PublicationTotowa, NL (US)
PublisherHumana Press
Number of pages15
ISBN (Electronic)978-1-59259-812-0
ISBN (Print)978-0-89603-873-8
Publication statusPublished - 2004

Publication series

NameMethods in molecular biology
PublisherHumana press
ISSN (Print)1064-3745


  • phagocytosis
  • apoptosis
  • B-lymphocytes
  • COS cells
  • cell line
  • cercopithecus aethiops
  • membrane proteins
  • macrophages


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