Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Irina Y. Yanina; Alexey P. Popov; Alexander V. Bykov; Igor V. Meglinski; Valery V. Tuchin

doi:10.1117/1.JBO.23.1.016003

Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Irina Y. Yanina^*, Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, Valery V. Tuchin

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.

Original language	English
Article number	016003
Journal	Journal of Biomedical Optics
Volume	23
Issue number	1
DOIs	https://doi.org/10.1117/1.JBO.23.1.016003
Publication status	Published - 2 Jan 2018

Bibliographical note

Keywords

Abbe refractometry
adipose tissue
heating
lipolysis
optical coherence tomography
phase transition
refractive index

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10.1117/1.JBO.23.1.016003Licence: CC BY 3.0

Monitoring of temperature-mediated phase transitionsFinal published version, 2.02 MB

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title = "Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry",

abstract = "Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.",

keywords = "Abbe refractometry, adipose tissue, heating, lipolysis, optical coherence tomography, phase transition, refractive index",

author = "Yanina, {Irina Y.} and Popov, {Alexey P.} and Bykov, {Alexander V.} and Meglinski, {Igor V.} and Tuchin, {Valery V.}",

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T1 - Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

AU - Yanina, Irina Y.

AU - Popov, Alexey P.

AU - Bykov, Alexander V.

AU - Meglinski, Igor V.

AU - Tuchin, Valery V.

PY - 2018/1/2

Y1 - 2018/1/2

N2 - Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.

AB - Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.

KW - Abbe refractometry

KW - adipose tissue

KW - heating

KW - lipolysis

KW - optical coherence tomography

KW - phase transition

KW - refractive index

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AN - SCOPUS:85040308119

SN - 1083-3668

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JO - Journal of Biomedical Optics

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ER -

Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Abstract

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Keywords

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