Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

Barbara Wegiel; David J. Gallo; Kathleen G. Raman; Jenny M. Karlsson; Brett Ozanich; Beek Y. Chin; Edith Tzeng; Shakil Ahmad; Asif Ahmed; Catherine J. Baty; Leo E. Otterbein

doi:10.1161/CIRCULATIONAHA.109.887695

Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

Barbara Wegiel, David J. Gallo, Kathleen G. Raman, Jenny M. Karlsson, Brett Ozanich, Beek Y. Chin, Edith Tzeng, Shakil Ahmad, Asif Ahmed, Catherine J. Baty, Leo E. Otterbein

Research output: Contribution to journal › Article › peer-review

Abstract

Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.

Original language	English
Pages (from-to)	537-548
Number of pages	12
Journal	Circulation
Volume	121
Issue number	4
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.109.887695
Publication status	Published - Feb 2010

Bibliographical note

Keywords

angioplasty
endothelium
nitric oxide synthase
signal transduction
stenosis

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10.1161/CIRCULATIONAHA.109.887695

Nitric Oxide-Dependent Bone Marrow Progenitor Mobilization
© 2010 American Heart Association, Inc.
Accepted author manuscript, 3.11 MB

Cite this

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title = "Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury",

abstract = "Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.",

keywords = "angioplasty, endothelium, nitric oxide synthase, signal transduction, stenosis",

author = "Barbara Wegiel and Gallo, {David J.} and Raman, {Kathleen G.} and Karlsson, {Jenny M.} and Brett Ozanich and Chin, {Beek Y.} and Edith Tzeng and Shakil Ahmad and Asif Ahmed and Baty, {Catherine J.} and Otterbein, {Leo E.}",

note = "{\textcopyright} 2010 American Heart Association, Inc.",

year = "2010",

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doi = "10.1161/CIRCULATIONAHA.109.887695",

language = "English",

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T1 - Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

AU - Wegiel, Barbara

AU - Gallo, David J.

AU - Raman, Kathleen G.

AU - Karlsson, Jenny M.

AU - Ozanich, Brett

AU - Chin, Beek Y.

AU - Tzeng, Edith

AU - Ahmad, Shakil

AU - Ahmed, Asif

AU - Baty, Catherine J.

AU - Otterbein, Leo E.

PY - 2010/2

Y1 - 2010/2

N2 - Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.

AB - Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.

KW - angioplasty

KW - endothelium

KW - nitric oxide synthase

KW - signal transduction

KW - stenosis

UR - http://www.scopus.com/inward/record.url?scp=76349103022&partnerID=8YFLogxK

UR - http://circ.ahajournals.org/content/121/4/537

U2 - 10.1161/CIRCULATIONAHA.109.887695

DO - 10.1161/CIRCULATIONAHA.109.887695

M3 - Article

C2 - 20083679

SN - 1524-4539

VL - 121

SP - 537

EP - 548

JO - Circulation

JF - Circulation

IS - 4

ER -

Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

Abstract

Bibliographical note

Keywords

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