Objective analysis of toric intraocular lens rotation and centration

James S Wolffsohn, Phillip J Buckhurst

Research output: Contribution to journalArticlepeer-review


PURPOSE: To assess the repeatability of an objective image analysis technique to determine intraocular lens (IOL) rotation and centration.
SETTING: Six ophthalmology clinics across Europe.
METHODS: One-hundred seven patients implanted with Akreos AO aspheric IOLs with orientation marks were imaged. Image quality was rated by a masked observer. The axis of rotation was determined from a line bisecting the IOL orientation marks. This was normalized for rotation of the eye between visits using the axis bisecting 2 consistent conjunctival vessels or iris features. The center of ovals overlaid to circumscribe the IOL optic edge and the pupil or limbus were compared to determine IOL centration. Intrasession repeatability was assessed in 40 eyes and the variability of repeated analysis examined.
RESULTS: Intrasession rotational stability of the IOL was ±0.79 degrees (SD) and centration was ±0.10 mm horizontally and ±0.10 mm vertically. Repeated analysis variability of the same image was ±0.70 degrees for rotation and ±0.20 mm horizontally and ±0.31 mm vertically for centration. Eye rotation (absolute) between visits was 2.23 ± 1.84 degrees (10%>5 degrees rotation) using one set of consistent conjunctival vessels or iris features and 2.03 ± 1.66 degrees (7%>5 degrees rotation) using the average of 2 sets (P =.13). Poorer image quality resulted in larger apparent absolute IOL rotation (r =-0.45,P<.001).
CONCLUSIONS: Objective analysis of digital retroillumination images allows sensitive assessment of IOL rotation and centration stability. Eye rotation between images can lead to significant errors if not taken into account. Image quality is important to analysis accuracy.
Original languageEnglish
Pages (from-to)778-782
Number of pages5
JournalJournal of Cataract and Refractive Surgery
Issue number5
Publication statusPublished - 10 May 2010
EventAnnual meeting of the Association for Research in Vision and Ophthalmology - Fort Lauderdale FL, United States
Duration: 1 May 2009 → …

Bibliographical note

NOTICE: this is the author’s version of a work that was accepted for publication in the Journal of Cataract & Refractive Surgery. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Wolffsohn, JS & Buckhurst, PJ, 'Objective analysis of toric intraocular lens rotation and centration', Journal of cataract and refractive surgery, vol 36, no. 5 (2010) DOI http://dx.doi.org/10.1016/j.jcrs.2009.12.027


  • astigmatism
  • blood vessels
  • conjunctiva
  • eye movements
  • humans
  • computer-assisted image processing
  • iris
  • intraocular lens implantation
  • intraocular lenses
  • orientation
  • rotation
  • visual acuity


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