Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

Ksenia Kandurova; Elena Potapova; Valery Shupletsov; Igor Kozlov; Evgeniya Seryogina; Viktor Dremin; Evgeny Zherebtsov; Alexander Alekseyev; Andrian Mamoshin; Andrey Dunaev

doi:10.1117/12.2526747

Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

Ksenia Kandurova^*, Elena Potapova, Valery Shupletsov, Igor Kozlov, Evgeniya Seryogina, Viktor Dremin, Evgeny Zherebtsov, Alexander Alekseyev, Andrian Mamoshin, Andrey Dunaev

^*Corresponding author for this work

Aston Institute of Photonic Technologies (AiPT)

Research output: Contribution to journal › Conference article › peer-review

Abstract

The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

Original language	English
Article number	110791C
Journal	Optics InfoBase Conference Papers
Volume	11079
DOIs	https://doi.org/10.1117/12.2526747
Publication status	Published - 22 Jul 2019
Event	European Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands Duration: 23 Jun 2019 → 25 Jun 2019

Bibliographical note

Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

Diffuse reflectance spectroscopy
Fine-needle aspiration biopsy
Fluorescence spectroscopy
Minimally invasive surgery
Optical biopsy
Tumor

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10.1117/12.2526747

Optical fine-needle biopsy approach for intraoperative multimodal
Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
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title = "Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery",

abstract = "The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.",

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author = "Ksenia Kandurova and Elena Potapova and Valery Shupletsov and Igor Kozlov and Evgeniya Seryogina and Viktor Dremin and Evgeny Zherebtsov and Alexander Alekseyev and Andrian Mamoshin and Andrey Dunaev",

note = "Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; European Conference on Biomedical Optics, ECBO_2019 ; Conference date: 23-06-2019 Through 25-06-2019",

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doi = "10.1117/12.2526747",

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T1 - Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

AU - Kandurova, Ksenia

AU - Potapova, Elena

AU - Shupletsov, Valery

AU - Kozlov, Igor

AU - Seryogina, Evgeniya

AU - Dremin, Viktor

AU - Zherebtsov, Evgeny

AU - Alekseyev, Alexander

AU - Mamoshin, Andrian

AU - Dunaev, Andrey

N1 - Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2019/7/22

Y1 - 2019/7/22

N2 - The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

AB - The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

KW - Diffuse reflectance spectroscopy

KW - Fine-needle aspiration biopsy

KW - Fluorescence spectroscopy

KW - Minimally invasive surgery

KW - Optical biopsy

KW - Tumor

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DO - 10.1117/12.2526747

M3 - Conference article

AN - SCOPUS:85084489599

VL - 11079

JO - Optics InfoBase Conference Papers

JF - Optics InfoBase Conference Papers

M1 - 110791C

T2 - European Conference on Biomedical Optics, ECBO_2019

Y2 - 23 June 2019 through 25 June 2019

ER -

Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

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Keywords

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