Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Keyphrases

• Amyloid beta 100%
• SH-SY5Y Cells 100%
• Oxidized Low-density Lipoprotein (ox-LDL) 100%
• Glutathione Depletion 100%
• Lipid Rafts 100%
• Lipoprotein Lipids 100%
• Lipids 37%
• Acid Sphingomyelinase 37%
• β-site APP-cleaving Enzyme 1 (BACE1) 37%
• Alzheimer's Disease 25%
• Neuronal Cells 25%
• Low-density Lipoprotein 25%
• Desipramine 25%
• Age-matched 12%
• Amyloid Precursor Protein 12%
• Native LDL 12%
• Oxidized Glutathione 12%
• Cholesterol 12%
• Lipid Metabolism 12%
• Later Life 12%
• N-acetylcysteine 12%
• Lethal Concentration 12%
• Dementia Patients 12%
• Reduced Glutathione 12%
• Total Lipids 12%
• Membrane Lipids 12%
• GSH Depletion 12%
• Membrane Remodeling 12%
• Membrane Rafts 12%
• 27-hydroxycholesterol 12%
• Dementia Risk 12%
• Secretase 12%
• Total Cholesterol Level 12%
• Lipoproteins LDL 12%

Biochemistry, Genetics and Molecular Biology

• Lipid 100%
• Amyloid Beta 100%
• Lipid Raft 100%
• Glutathione 100%
• Low-Density Lipoprotein 100%
• Sphingomyelin Phosphodiesterase 60%
• Acid Sphingomyelinase 60%
• Amyloid Precursor Protein 20%
• Lipid Metabolism 20%
• Membrane Lipid 20%
• Cholesterol Blood Level 20%
• 27-Hydroxycholesterol 20%
• Secretase 20%
• Total Cholesterol Level 20%
• Blood Plasma 20%
• Amyloid Protein 20%
• Acetylcysteine 20%

Immunology and Microbiology

• Lipid Raft 100%
• Blood Plasma 50%
• Precursor 50%
• Lipid Metabolism 50%
• Cholesterol Blood Level 50%
• Total Cholesterol Level 50%