Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism

P. Edwards; R.J. Cattell; J.A. Blair; Richard A. Armstrong

Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism

P. Edwards, R.J. Cattell, J.A. Blair, Richard A. Armstrong

Research output: Unpublished contribution to conference › Unpublished Conference Paper › peer-review

Abstract

The P2 visual evoked response in man has a cholinergic component while the P100 response has not. The P100 latency is significantly decreased after an oral dose of phenylalanine in man while the P2 signal is unaffected. Analyses of the P100 decrease shows no correlation with tyrosine levels but a significant positive correlation with plasma ane urine levels. A small group shows a P100 delay which correlated with increased neopterin levels only. Increased plasma total biopterins in man following a phenylalanine dose are due to rapidly increased tetrahydrobiopterin synthesis in the liver.

Original language	English
Publication status	Unpublished - 1993
Event	12th International Winter Workshop on Biochemical and Clinical Aspects of Pteridines - St. Christoph, Arlberg, Austria Duration: 1 Feb 1993 → …

Workshop

Workshop	12th International Winter Workshop on Biochemical and Clinical Aspects of Pteridines
Country/Territory	Austria
City	St. Christoph, Arlberg
Period	1/02/93 → …

Bibliographical note

Abstract appearing in Pteridines 4:P96-97, 0933-4807.

Keywords

visual evoked response
P100
P2
plasma total biopterins
tetrahydrobiopterin synthesis
liver

Cite this

@conference{0be5ed716a65428e8f343e790a2969ab,

title = "Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism",

abstract = "The P2 visual evoked response in man has a cholinergic component while the P100 response has not. The P100 latency is significantly decreased after an oral dose of phenylalanine in man while the P2 signal is unaffected. Analyses of the P100 decrease shows no correlation with tyrosine levels but a significant positive correlation with plasma ane urine levels. A small group shows a P100 delay which correlated with increased neopterin levels only. Increased plasma total biopterins in man following a phenylalanine dose are due to rapidly increased tetrahydrobiopterin synthesis in the liver.",

keywords = "visual evoked response, P100, P2, plasma total biopterins, tetrahydrobiopterin synthesis, liver",

author = "P. Edwards and R.J. Cattell and J.A. Blair and Armstrong, {Richard A.}",

note = "Abstract appearing in Pteridines 4:P96-97, 0933-4807.; 12th International Winter Workshop on Biochemical and Clinical Aspects of Pteridines ; Conference date: 01-02-1993",

year = "1993",

language = "English",

}

Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism. / Edwards, P.; Cattell, R.J.; Blair, J.A. et al.
1993. Paper presented at 12th International Winter Workshop on Biochemical and Clinical Aspects of Pteridines, St. Christoph, Arlberg, Austria.

Research output: Unpublished contribution to conference › Unpublished Conference Paper › peer-review

TY - CONF

T1 - Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism

AU - Edwards, P.

AU - Cattell, R.J.

AU - Blair, J.A.

AU - Armstrong, Richard A.

N1 - Abstract appearing in Pteridines 4:P96-97, 0933-4807.

PY - 1993

Y1 - 1993

N2 - The P2 visual evoked response in man has a cholinergic component while the P100 response has not. The P100 latency is significantly decreased after an oral dose of phenylalanine in man while the P2 signal is unaffected. Analyses of the P100 decrease shows no correlation with tyrosine levels but a significant positive correlation with plasma ane urine levels. A small group shows a P100 delay which correlated with increased neopterin levels only. Increased plasma total biopterins in man following a phenylalanine dose are due to rapidly increased tetrahydrobiopterin synthesis in the liver.

AB - The P2 visual evoked response in man has a cholinergic component while the P100 response has not. The P100 latency is significantly decreased after an oral dose of phenylalanine in man while the P2 signal is unaffected. Analyses of the P100 decrease shows no correlation with tyrosine levels but a significant positive correlation with plasma ane urine levels. A small group shows a P100 delay which correlated with increased neopterin levels only. Increased plasma total biopterins in man following a phenylalanine dose are due to rapidly increased tetrahydrobiopterin synthesis in the liver.

KW - visual evoked response

KW - P100

KW - P2

KW - plasma total biopterins

KW - tetrahydrobiopterin synthesis

KW - liver

M3 - Unpublished Conference Paper

T2 - 12th International Winter Workshop on Biochemical and Clinical Aspects of Pteridines

Y2 - 1 February 1993

ER -

Pattern visual evoked potentials in man and tetrahydrobiopterin metabolism

Abstract

Workshop

Bibliographical note

Keywords

Fingerprint

Cite this