Physicochemical properties of hydrogels for use in ophthalmology

B.J. Tighe; A. Mann

doi:10.1016/B978-0-08-100147-9.00004-3

Physicochemical properties of hydrogels for use in ophthalmology

B.J. Tighe^*, A. Mann

^*Corresponding author for this work

Chemical Engineering & Applied Chemistry

Research output: Chapter in Book/Published conference output › Chapter

Abstract

This chapter deals with the physicochemical aspects of structure-property relationships in synthetic hydrogels, with particular reference to their application in optometry and ophthalmology. It demonstrates the ways in which the amount of water contained in the hydrogel network can be manipulated by changes in copolymer composition and illustrates the advantages and limitations imposed by use of water as a means of influencing surface, transport and mechanical properties of the gel. The chapter then illustrates how this basic understanding has formed a platform for the development of synthetic interpenetrating networks and macroporous materials, and of hybrids of natural and synthetic hydrogels. The behaviour of these more complex systems is not so centrally dominated by the equilibrium water content as is the case with homogeneous synthetic hydrogels, thus providing advantageous ways of extending the properties and applications of these interesting materials.

Original language	English
Title of host publication	Biomaterials and regenerative medicine in ophthalmology
Editors	Traian V. Chirila, Damien G. Harkin
Place of Publication	London (UK)
Publisher	Woodhead
Pages	75-100
Number of pages	26
Edition	2nd
ISBN (Electronic)	978-0-08-100184-4
ISBN (Print)	978-0-08-100147-9
DOIs	https://doi.org/10.1016/B978-0-08-100147-9.00004-3
Publication status	Published - 21 Apr 2016

Publication series

Name	Woodhead Publishing Series in Biomaterials
Publisher	Woodhead Publishing
Number	112

Keywords

equilibrium water content
hydrogels
interpenetrating networks
macroporous hydrogels
oxygen permeability
surface energy

Access to Document

10.1016/B978-0-08-100147-9.00004-3

Cite this

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title = "Physicochemical properties of hydrogels for use in ophthalmology",

abstract = "This chapter deals with the physicochemical aspects of structure-property relationships in synthetic hydrogels, with particular reference to their application in optometry and ophthalmology. It demonstrates the ways in which the amount of water contained in the hydrogel network can be manipulated by changes in copolymer composition and illustrates the advantages and limitations imposed by use of water as a means of influencing surface, transport and mechanical properties of the gel. The chapter then illustrates how this basic understanding has formed a platform for the development of synthetic interpenetrating networks and macroporous materials, and of hybrids of natural and synthetic hydrogels. The behaviour of these more complex systems is not so centrally dominated by the equilibrium water content as is the case with homogeneous synthetic hydrogels, thus providing advantageous ways of extending the properties and applications of these interesting materials.",

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author = "B.J. Tighe and A. Mann",

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doi = "10.1016/B978-0-08-100147-9.00004-3",

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AU - Mann, A.

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N2 - This chapter deals with the physicochemical aspects of structure-property relationships in synthetic hydrogels, with particular reference to their application in optometry and ophthalmology. It demonstrates the ways in which the amount of water contained in the hydrogel network can be manipulated by changes in copolymer composition and illustrates the advantages and limitations imposed by use of water as a means of influencing surface, transport and mechanical properties of the gel. The chapter then illustrates how this basic understanding has formed a platform for the development of synthetic interpenetrating networks and macroporous materials, and of hybrids of natural and synthetic hydrogels. The behaviour of these more complex systems is not so centrally dominated by the equilibrium water content as is the case with homogeneous synthetic hydrogels, thus providing advantageous ways of extending the properties and applications of these interesting materials.

AB - This chapter deals with the physicochemical aspects of structure-property relationships in synthetic hydrogels, with particular reference to their application in optometry and ophthalmology. It demonstrates the ways in which the amount of water contained in the hydrogel network can be manipulated by changes in copolymer composition and illustrates the advantages and limitations imposed by use of water as a means of influencing surface, transport and mechanical properties of the gel. The chapter then illustrates how this basic understanding has formed a platform for the development of synthetic interpenetrating networks and macroporous materials, and of hybrids of natural and synthetic hydrogels. The behaviour of these more complex systems is not so centrally dominated by the equilibrium water content as is the case with homogeneous synthetic hydrogels, thus providing advantageous ways of extending the properties and applications of these interesting materials.

KW - equilibrium water content

KW - hydrogels

KW - interpenetrating networks

KW - macroporous hydrogels

KW - oxygen permeability

KW - surface energy

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M3 - Chapter

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SN - 978-0-08-100147-9

T3 - Woodhead Publishing Series in Biomaterials

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BT - Biomaterials and regenerative medicine in ophthalmology

A2 - Chirila, Traian V.

A2 - Harkin, Damien G.

PB - Woodhead

CY - London (UK)

ER -

Physicochemical properties of hydrogels for use in ophthalmology

Abstract

Publication series

Keywords

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