Pilot studies of age-related changes in blood perfusion in two different types of skin

Yulia Loktionova, Elena Zharkikh, Igor Kozlov, Evgeny Zherebtsov, Svetlana Bryanskaya, Angelina Zherebtsova, Victor Sidorov, Sergei Sokolovski, Andrey Dunaev, Edik Rafailov, Valery V. Tuchin, Elina A. Genina (Editor)

Research output: Contribution to journalConference articlepeer-review


Laser Doppler flowmetry (LDF) was utilized to assess age-related changes in the blood microcirculation at the skin sites with different morphology and regulation. The LDF signals obtained from the glabrous skin of the middle finger pad and nonglabrous skin on the dorsal wrist surface were analyzed. Statistically higher baseline perfusion was observed in the zone with glabrous skin in the older group of volunteers compared to younger participants. Observed site-specific and age-related differences in perfusion can be used in the future experimental design for the studies of the blood microcirculation system in patients with different pathologies.
Original languageEnglish
Article number110650S
JournalProceedings of SPIE - International Society for Optical Engineering
Publication statusPublished - 3 Jun 2019
EventSaratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine - Saratov, Russian Federation
Duration: 24 Sept 201829 Sept 2018

Bibliographical note

Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Funding: Russian Science Foundation (the research project 18-79-00237).


  • Ageing
  • Blood microcirculation
  • Laser Doppler flowmetry


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