Polymer membranes in clinical sensor applications. III. Hydrogels as reactive matrix membranes in fibre optic sensors

M. L. Davies; S. M. Murphy; C. J. Hamilton; B. J. Tighe

doi:10.1016/0142-9612(92)90149-I

Polymer membranes in clinical sensor applications. III. Hydrogels as reactive matrix membranes in fibre optic sensors

M. L. Davies, S. M. Murphy, C. J. Hamilton, B. J. Tighe^*

^*Corresponding author for this work

Chemical Engineering & Applied Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The potential of hydrogel copolymer membranes in clinical sensors, based on fibre optics, is addressed. The particular properties of the membranes of relevance in this application are the ease of refractive index modulation and the potential of the hydrogel to act as a permselective barrier in which a colorimetric agent may be immobilized. The results presented illustrate the complexity of colorimetric and refractive index effects together with their dependence on pH and tonicity for hydrogels of a given composition range. The incorporation of an acryloyl-functionalized reagent (bromopyrogallol red) is used to illustrate the way in which a working pH sensor based on these combined properties may be designed and fabricated.

Original language	English
Pages (from-to)	991-999
Number of pages	9
Journal	Biomaterials
Volume	13
Issue number	14
DOIs	https://doi.org/10.1016/0142-9612(92)90149-I
Publication status	Published - 1992

Keywords

fibre optic sensors
hydrogels
Membranes

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10.1016/0142-9612(92)90149-I

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abstract = "The potential of hydrogel copolymer membranes in clinical sensors, based on fibre optics, is addressed. The particular properties of the membranes of relevance in this application are the ease of refractive index modulation and the potential of the hydrogel to act as a permselective barrier in which a colorimetric agent may be immobilized. The results presented illustrate the complexity of colorimetric and refractive index effects together with their dependence on pH and tonicity for hydrogels of a given composition range. The incorporation of an acryloyl-functionalized reagent (bromopyrogallol red) is used to illustrate the way in which a working pH sensor based on these combined properties may be designed and fabricated.",

keywords = "fibre optic sensors, hydrogels, Membranes",

author = "Davies, {M. L.} and Murphy, {S. M.} and Hamilton, {C. J.} and Tighe, {B. J.}",

year = "1992",

doi = "10.1016/0142-9612(92)90149-I",

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AU - Davies, M. L.

AU - Murphy, S. M.

AU - Hamilton, C. J.

AU - Tighe, B. J.

PY - 1992

Y1 - 1992

N2 - The potential of hydrogel copolymer membranes in clinical sensors, based on fibre optics, is addressed. The particular properties of the membranes of relevance in this application are the ease of refractive index modulation and the potential of the hydrogel to act as a permselective barrier in which a colorimetric agent may be immobilized. The results presented illustrate the complexity of colorimetric and refractive index effects together with their dependence on pH and tonicity for hydrogels of a given composition range. The incorporation of an acryloyl-functionalized reagent (bromopyrogallol red) is used to illustrate the way in which a working pH sensor based on these combined properties may be designed and fabricated.

AB - The potential of hydrogel copolymer membranes in clinical sensors, based on fibre optics, is addressed. The particular properties of the membranes of relevance in this application are the ease of refractive index modulation and the potential of the hydrogel to act as a permselective barrier in which a colorimetric agent may be immobilized. The results presented illustrate the complexity of colorimetric and refractive index effects together with their dependence on pH and tonicity for hydrogels of a given composition range. The incorporation of an acryloyl-functionalized reagent (bromopyrogallol red) is used to illustrate the way in which a working pH sensor based on these combined properties may be designed and fabricated.

KW - fibre optic sensors

KW - hydrogels

KW - Membranes

UR - https://www.sciencedirect.com/science/article/abs/pii/014296129290149I

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AN - SCOPUS:0026439858

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SP - 991

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JO - Biomaterials

JF - Biomaterials

IS - 14

ER -

Polymer membranes in clinical sensor applications. III. Hydrogels as reactive matrix membranes in fibre optic sensors

Abstract

Keywords

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