Randomized crossover trial of silicone hydrogel presbyopic contact lenses

Ahmed Sivardeen, Deborah Laughton, James S. Wolffsohn

Research output: Contribution to journalArticlepeer-review


PURPOSE: To assess the performance of four commercially available silicone hydrogel multifocal monthly contact lens designs against monovision.

METHODS: A double-masked randomized crossover trial of Air Optix Aqua multifocal, PureVision 2 for Presbyopia, Acuvue OASYS for Presbyopia, Biofinity multifocal, and monovision with Biofinity contact lenses was conducted on 35 presbyopes (54.3 ± 6.2 years). After 4 weeks of wear, visual performance was quantified by high- and low-contrast visual acuity under photopic and mesopic conditions, reading speed, defocus curves, stereopsis, halometry, aberrometry, Near Activity Visual Questionnaire rating, and subjective quality of vision scoring. Bulbar, limbal, and palpebral hyperemia and corneal staining were graded to monitor the impact of each contact lens on ocular physiology.

RESULTS: High-contrast photopic visual acuity (p = 0.102), reading speed (F = 1.082, p = 0.368), and aberrometry (F = 0.855, p = 0.493) were not significantly different between presbyopic lens options. Defocus curve profiles (p <0.001), stereopsis (p <0.001), halometry (F = 4.101, p = 0.004), Near Activity Visual Questionnaire (F = 3.730, p = 0.007), quality of vision (p = 0.002), bulbar hyperemia (p = 0.020), and palpebral hyperemia (p = 0.012) differed significantly between lens types, with the Biofinity multifocal lens design principal (center-distance lens was fitted to the dominant eye and a center-near lens to the nondominant eye) typically outperforming the other lenses.

CONCLUSIONS: Although ocular aberration variation between individuals largely masks the differences in optics between current multifocal contact lens designs, certain design strategies can outperform monovision, even in early presbyopes.

Original languageEnglish
Pages (from-to)141–149
Number of pages9
JournalOptometry and Vision Science
Issue number2
Early online date22 Dec 2015
Publication statusPublished - Feb 2016

Bibliographical note

This is a non-final version of an article published in final form in Sivardeen, A., Laughton, D., & Wolffsohn, J. S. (2016). Randomized crossover trial of silicone hydrogel presbyopic contact lenses. Optometry and vision science, 93(2), 141–149.


  • contact lenses
  • multifocal
  • simultaneous images
  • monovision
  • presbyopia


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