Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production

Keyphrases

• Bioscience 50%
• Drug pipeline 100%
• Error Optimization 50%
• Functional Information 50%
• High Yielding 50%
• Host Response 50%
• Identified Genes 50%
• Improved Production 50%
• Mechanistic Details 50%
• Membrane Protein 50%
• Membrane Protein Biogenesis 100%
• Microarray Technology 100%
• New Drug Targets 50%
• Production Strain 50%
• Recombinant Membrane Protein 50%
• Recombinant Protein Production 50%
• Structural Biology 50%
• Structural Information 50%
• Structure-based Drug Design 50%
• Transcriptome Analysis 50%
• Trial-and-error 50%
• Yeast Cell Factories 50%

Biochemistry, Genetics and Molecular Biology

• Gene Expression Profiling 50%
• Hope 50%
• Immune Response 50%
• Membrane Protein 100%
• Recombinant Protein 50%
• Transmembrane Protein 100%