Spray dried combinations of lactoferrin with antibiotics appear superior to monotherapy for reducing biofilm formation by pseudomonas aeruginosa

Keyphrases

• Pseudomonas Aeruginosa (P. aeruginosa) 100%
• Antibiotics 100%
• Monotherapy 100%
• Lactoferrin 100%
• Biofilm Formation 100%
• Biofilm 50%
• Cystic Fibrosis 45%
• Gentamicin 40%
• Apo-lactoferrin 40%
• Tobramycin 35%
• Spray Drying 25%
• Pseudomonas Aeruginosa Biofilm 25%
• Incubation 20%
• Bacterial Cells 20%
• Aliquot 15%
• Aminoglycosides 15%
• Moisture Content 10%
• AstA 10%
• Fe3+ 10%
• Acetic Acid 10%
• Temps 10%
• Combination Therapy 10%
• Cell Viability 10%
• Chloride Acid 10%
• Airway 10%
• Aerosolised 10%
• Magnesium Chloride 10%
• Crystal Violet Staining 10%
• Antimicrobial Peptides 10%
• PAO1 10%
• Pseudomonas Aeruginosa PAO1 10%
• Lung Infection 10%
• Viability Assay 10%
• Casamino Acids 10%
• Broth 10%
• Antibiotic Combination 10%
• Deionized Water 5%
• Pharmacology 5%
• Pharmacy 5%
• Iron Binding 5%
• Incubation Period 5%
• Birmingham UK 5%
• Microbiology 5%
• Dialysis 5%
• Room Temperature 5%
• Birmingham 5%
• Chelates 5%
• Treatment Strategy 5%
• Virulence Factors 5%
• Crystal Violet 5%
• Antibiotic Resistance 5%
• Microplate Reader 5%
• Chimera 5%
• Current Treatment 5%
• Carroll 5%
• Particle Size 5%
• Growth Conditions 5%
• Colony Forming Units 5%
• Life Sciences 5%
• Health Sciences 5%
• Anaerobic Conditions 5%
• Thermo 5%
• Sodium Acetate 5%
• Absorbance 5%
• Viable Cells 5%
• Spectroscopic Measurement 5%
• Bacterial Growth 5%
• Campina 5%
• Lactoferrin-derived Peptides 5%
• Antibiotic Treatment 5%
• Agar Plate 5%
• Lactoferricin 5%
• Sodium Dihydrogen Phosphate 5%
• Drying Parameters 5%
• Planktonic Bacteria 5%
• Mean Weight Diameter 5%
• Major Contributor 5%
• Anti-infective 5%
• Atomic Absorption Spectrometry 5%
• Pseudomonas Aeruginosa Infection 5%
• Outlet Temperature 5%
• Spray Rate 5%
• Ferric Ion 5%
• Micron Particles 5%
• Consensus Document 5%
• Pump Settings 5%
• Airway Epithelial Cells 5%
• Fibrosis Therapy 5%
• High Morbidity 5%
• High Mortality 5%
• Air Flow Rate 5%
• Aspirator 5%
• Advanced Drug Delivery 5%
• Anaerobic Biofilm 5%
• Biofilm Detection 5%
• Overnight Culture 5%
• Planktonic Growth 5%
• Mueller-Hinton Agar 5%
• Aerosol 5%
• Bacterial Strains 5%
• Lower Airways 5%
• Inlet Temperature 5%
• Strain Conditions 5%
• Friesland 5%
• 96-well 5%
• Aqueous Suspension 5%
• Biofilm Infection 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Pseudomonas aeruginosa 100%
• Antibiotic Agent 100%
• Monotherapy 100%
• Lactoferrin 100%
• Cystic Fibrosis 31%
• Gentamicin 27%
• Tobramycin 24%
• Ferric Ion 10%
• Potassium Acetate 10%
• Crystal Violet 10%
• Antibiotics 10%
• Aminoglycoside 10%
• Combination Therapy 6%
• Cell Viability 6%
• Acetylsalicylic Acid 6%
• Casamino Acid 6%
• Magnesium Chloride 6%
• Polypeptide Antibiotic Agent 6%
• Viability Assay 6%
• Lung Infection 6%
• Ethylenediaminetetraacetic Acid 3%
• Incubation Time 3%
• Infection 3%
• Virulence Factor 3%
• Antibiotic Resistance 3%
• Deionized Water 3%
• Sodium Dihydrogen Phosphate 3%
• Lactoferricin 3%
• Pseudomonas Infection 3%
• Agar 3%
• Iron Chelate 3%