Studies of age-related changes in blood perfusion coherence using wearable blood perfusion sensor system

Yulia I. Loktionova, Evgeny A. Zherebtsov, Elena V. Zharkikh, Igor O. Kozlov, Angelina I. Zherebtsova, Victor V. Sidorov, Sergei Sokolovski, Ilya E. Rafailov, Andrey V. Dunaev, Edik U. Rafailov, Arjen Amelink (Editor), Seemantini K. Nadkarni (Editor)

Research output: Contribution to journalConference articlepeer-review


Laser Doppler flowmetry (LDF) was used for detection of age-related changes in the blood microcirculation. The LDF signal was simultaneously recorded from the 3rd fingers' pads of both hands. Amplitudes of the blood flow oscillations and wavelet coherence of the signals were used for the data analysis. A statistical difference in the synchronisation of myogenic oscillations was found between the two studied age groups. Myogenic oscillations of blood perfusion in the younger group had a higher wavelet coherence parameter than in the older group. Observed site-specific and age-related differences in blood perfusion can be used in the future in the design of experimental studies of the blood microcirculation system in patients with different pathologies.
Original languageEnglish
Pages (from-to)6
JournalProceedings of SPIE - International Society for Optical Engineering
Publication statusPublished - 22 Jul 2019
EventNovel Biophotonics Techniques and Applications - Munich, Germany
Duration: 23 Jun 201927 Jun 2019

Bibliographical note

Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Funding: Russian Science Foundation (the research project 18-79-00237), grant of Academy of Finland No.318281.


  • ageing
  • blood ow oscillations
  • laser Doppler owmetry
  • microcirculation
  • wavelet coherence


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