TY - JOUR
T1 - Synthesis and evaluation of scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports
AU - McCairn, Mark C.
AU - Hine, Anna V.
AU - Sutherland, Andrew J.
PY - 2003
Y1 - 2003
N2 - Co-polymerisation of α-styryl-poly(ethylene glycol)300, α,ω-bis(styryl)-penta(ethylene glycol) and 2,5-diphenyl-4-(4′-vinylbenzyl)oxazole in varying molar ratios resulted in the production of chemically functionalised scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports. These materials are compatible with both aqueous and organic solvents, and possess the ability to scintillate efficiently in the presence of ionising radiation, even after prolonged and repeated exposure to organic solvents. The utility of POP-Sc supports in both solid-phase peptide chemistry and a functional scintillation proximity assay has been exemplified.
AB - Co-polymerisation of α-styryl-poly(ethylene glycol)300, α,ω-bis(styryl)-penta(ethylene glycol) and 2,5-diphenyl-4-(4′-vinylbenzyl)oxazole in varying molar ratios resulted in the production of chemically functionalised scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports. These materials are compatible with both aqueous and organic solvents, and possess the ability to scintillate efficiently in the presence of ionising radiation, even after prolonged and repeated exposure to organic solvents. The utility of POP-Sc supports in both solid-phase peptide chemistry and a functional scintillation proximity assay has been exemplified.
UR - http://www.scopus.com/inward/record.url?scp=0037323454&partnerID=8YFLogxK
UR - http://www.rsc.org/Publishing/Journals/JM/article.asp?doi=b210421k
U2 - 10.1039/b210421k
DO - 10.1039/b210421k
M3 - Article
SN - 0959-9428
VL - 13
SP - 225
EP - 231
JO - Journal of Materials Chemistry
JF - Journal of Materials Chemistry
IS - 2
ER -