The association between sleeping time and metabolic syndrome features among older adults living in Mediterranean region. The MEDIS study.

Ekavi Georgousopoulou, Nathan D'Cunha, Duane Mellor, Stefanos Tyrovolas, Nenad Naumovski, Alexandra Foscolou, Vassoliki Bountzioka, Efthimios Gotsis, George Metallinos, Dimitra Tyrovola, Suzanne Piscopo, Giuseppe Valacchi, Nikos Tsakountakis, Akis Zeimbekis, Josep-Antoni Tur, Antonia-Leda Matalas, Evangelos Polychronopoulos, Chritos Lionis, Labros Sidossis, Demosthenes PanagiotakosMEDIS Study Group

Research output: Contribution to journalArticlepeer-review


Background: Metabolic Syndrome (MetS) as a combination of features has been known to significantly increase Cardiovascular Disease (CVD) risk, whilst MetS presence is linked to lifestyle parameters including physical activity and dietary habits; recently, the potential impact of sleeping habits has also become an issue under consideration. The aim of this study was to investigate the role of sleep quantity in several MetS components.
Methods: Design:Cross-sectional observational study. Setting: 26 Mediterranean islands and the rural Mani region (Peloponnesus) of Greece. Participants: during 2005-2017, 3130 older (aged 65-100 years) Mediterranean residents were voluntarily enrolled. Measurements: Dietary habits (including MedDietScore assessment), physical activity status, socio-demographic characteristics, lifestyle parameters (sleeping and smoking habits) and clinical profile aspects including Metabolic Syndrome (MetS) components (i.e., waist circumference, systolic and diastolic blood pressure, fasting glucose, triglycerides, LDL and HDL-cholesterol) were derived through standard procedures.
Results: The number of daily hours of sleep was independently associated with greater waist circumference (b coefficient per 1 hour=0.91, 95% Confidence Interval (CI); 0.34, 1.49), higher LDL-cholesterol levels (b per 1 hour=3.84, 95%CI; 0.63, 7.05) and lower diastolic blood pressure levels (b per 1 hour=-0.98, 95%CI; - 1.57, -0.39) after adjusting for participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides, HDL-cholesterol and systolic blood pressure.
Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly inviduals, and further research is needed to identify the paths through which sleep quantity is linked to MetS features in different age-groups.
Original languageEnglish
JournalMetabolic Syndrome and Related Disorders
Issue number1
Early online date22 Jan 2018
Publication statusPublished - 1 Feb 2018

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