The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski; Edik U. Rafailov

doi:10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Victor V. Dremin, Victor V. Sidorov, Alexander I. Krupatkin, Gagik R. Galstyan, Irina N. Novikova, Angelina I. Zherebtsova, Evgeny A. Zherebtsov, Andrey V. Dunaev, Zera N. Abdulvapova, Karina S. Litvinova, Ilya E. Rafailov, Sergei G. Sokolovski, Edik U. Rafailov

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

Original language	English
Title of host publication	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Editors	Tuan Vo-Dinh, Anita Mahadevan-Jansen, Warren S. Grundfest
Place of Publication	Bellingham, WA (US)
Publisher	SPIE
Number of pages	7
ISBN (Print)	978-1-6284-1932-0
DOIs	https://doi.org/10.1117/12.2212758
Publication status	Published - 7 Mar 2016
Event	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV - San Francisco, United States Duration: 14 Feb 2016 → 16 Feb 2016

Publication series

Name	SPIE Proceedings
Publisher	SPIE
Volume	9698
ISSN (Print)	0277-786X
ISSN (Electronic)	2410-9045

Name	Progress in Biomedical Optics and Imaging
Publisher	Spie
Number	10
Volume	17
ISSN (Print)	1605-7422

Conference

Conference	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Country/Territory	United States
City	San Francisco
Period	14/02/16 → 16/02/16

Bibliographical note

Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016).

Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

DOI: http://dx.doi.org/10.1117/12.2212758

Keywords

diabetic foot syndrome
fluorescence spectroscopy
laser Doppler flowmetry
microcirculation
redox ratio

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10.1117/12.2212758

Blood perfusion and NADH_FAD content combined analysis
Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016). Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2212758
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http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=2501708

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Dremin, V. V., Sidorov, V. V., Krupatkin, A. I., Galstyan, G. R., Novikova, I. N., Zherebtsova, A. I., Zherebtsov, E. A., Dunaev, A. V., Abdulvapova, Z. N., Litvinova, K. S., Rafailov, I. E., Sokolovski, S. G., & Rafailov, E. U. (2016). The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. In T. Vo-Dinh, A. Mahadevan-Jansen, & W. S. Grundfest (Eds.), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV Article 969810 (SPIE Proceedings; Vol. 9698), (Progress in Biomedical Optics and Imaging; Vol. 17, No. 10). SPIE. https://doi.org/10.1117/12.2212758

Dremin, Victor V. ; Sidorov, Victor V. ; Krupatkin, Alexander I. et al. / The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV. editor / Tuan Vo-Dinh ; Anita Mahadevan-Jansen ; Warren S. Grundfest. Bellingham, WA (US) : SPIE, 2016. (SPIE Proceedings). (Progress in Biomedical Optics and Imaging; 10).

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title = "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot",

abstract = "Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.",

keywords = "diabetic foot syndrome, fluorescence spectroscopy, laser Doppler flowmetry, microcirculation, redox ratio",

author = "Dremin, {Victor V.} and Sidorov, {Victor V.} and Krupatkin, {Alexander I.} and Galstyan, {Gagik R.} and Novikova, {Irina N.} and Zherebtsova, {Angelina I.} and Zherebtsov, {Evgeny A.} and Dunaev, {Andrey V.} and Abdulvapova, {Zera N.} and Litvinova, {Karina S.} and Rafailov, {Ilya E.} and Sokolovski, {Sergei G.} and Rafailov, {Edik U.}",

note = "Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; {"}The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot{"}, Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016). Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2212758; Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV ; Conference date: 14-02-2016 Through 16-02-2016",

year = "2016",

month = mar,

day = "7",

doi = "10.1117/12.2212758",

language = "English",

isbn = "978-1-6284-1932-0",

series = "SPIE Proceedings",

publisher = "SPIE",

editor = "Tuan Vo-Dinh and Anita Mahadevan-Jansen and Grundfest, {Warren S.}",

booktitle = "Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV",

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Dremin, VV, Sidorov, VV, Krupatkin, AI, Galstyan, GR, Novikova, IN, Zherebtsova, AI, Zherebtsov, EA, Dunaev, AV, Abdulvapova, ZN, Litvinova, KS, Rafailov, IE, Sokolovski, SG & Rafailov, EU 2016, The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. in T Vo-Dinh, A Mahadevan-Jansen & WS Grundfest (eds), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV., 969810, SPIE Proceedings, vol. 9698, Progress in Biomedical Optics and Imaging, no. 10, vol. 17, SPIE, Bellingham, WA (US), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, San Francisco, United States, 14/02/16. https://doi.org/10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. / Dremin, Victor V.; Sidorov, Victor V.; Krupatkin, Alexander I. et al.
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV. ed. / Tuan Vo-Dinh; Anita Mahadevan-Jansen; Warren S. Grundfest. Bellingham, WA (US): SPIE, 2016. 969810 (SPIE Proceedings; Vol. 9698), (Progress in Biomedical Optics and Imaging; Vol. 17, No. 10).

Research output: Chapter in Book/Published conference output › Conference publication

TY - GEN

T1 - The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

AU - Dremin, Victor V.

AU - Sidorov, Victor V.

AU - Krupatkin, Alexander I.

AU - Galstyan, Gagik R.

AU - Novikova, Irina N.

AU - Zherebtsova, Angelina I.

AU - Zherebtsov, Evgeny A.

AU - Dunaev, Andrey V.

AU - Abdulvapova, Zera N.

AU - Litvinova, Karina S.

AU - Rafailov, Ilya E.

AU - Sokolovski, Sergei G.

AU - Rafailov, Edik U.

N1 - Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016). Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2212758

PY - 2016/3/7

Y1 - 2016/3/7

N2 - Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

AB - Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

KW - diabetic foot syndrome

KW - fluorescence spectroscopy

KW - laser Doppler flowmetry

KW - microcirculation

KW - redox ratio

UR - http://www.scopus.com/inward/record.url?scp=84973908831&partnerID=8YFLogxK

U2 - 10.1117/12.2212758

DO - 10.1117/12.2212758

M3 - Conference publication

AN - SCOPUS:84973908831

SN - 978-1-6284-1932-0

T3 - SPIE Proceedings

BT - Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV

A2 - Vo-Dinh, Tuan

A2 - Mahadevan-Jansen, Anita

A2 - Grundfest, Warren S.

PB - SPIE

CY - Bellingham, WA (US)

T2 - Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV

Y2 - 14 February 2016 through 16 February 2016

ER -

Dremin VV, Sidorov VV, Krupatkin AI, Galstyan GR, Novikova IN, Zherebtsova AI et al. The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. In Vo-Dinh T, Mahadevan-Jansen A, Grundfest WS, editors, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV. Bellingham, WA (US): SPIE. 2016. 969810. (SPIE Proceedings). (Progress in Biomedical Optics and Imaging; 10). doi: 10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

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Publication series

Conference

Bibliographical note

Keywords

Access to Document

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