The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch

Neuroscience

• C-Terminus 100%
• 14-3-3 Protein 100%
• Adenosine Triphosphate 50%
• Cofactor 25%
• In Vitro 25%
• Kinase 25%
• Binding Site 25%
• Cell Surface Receptor 25%
• Protein Function 25%
• Protein-Protein Interaction 25%
• Cell Survival 25%
• Cell Proliferation 25%
• Cell Migration 25%
• MAPK/ERK Pathway 25%
• Raf Kinase 25%

Keyphrases

• C-terminus 100%
• RAF1 100%
• Activation Switches 100%
• Phosphorylation 60%
• 14-3-3 Protein 40%
• Binding Site 10%
• Cell Surface Receptor 10%
• Protein Kinase 10%
• Cell Survival 10%
• Cell Proliferation 10%
• Cell Migration 10%
• Protein Function 10%
• In Vitro Activity 10%
• ATP Binding 10%
• Protein-protein Interaction 10%
• ERK Pathway 10%
• Conformational Alteration 10%
• ERK MAPK 10%
• Catalytic Activity 10%

Biochemistry, Genetics and Molecular Biology

• C-Terminus 100%
• 14-3-3 Protein 100%
• Adenosine Triphosphate 50%
• Kinase 25%
• Phosphotransferase 25%
• Binding Site 25%
• Cell Surface Receptor 25%
• Cell Survival 25%
• Cell Proliferation 25%
• Cell Migration 25%
• Protein Function 25%
• Protein-Protein Interaction 25%
• Raf Kinase 25%
• MAPK/ERK Pathway 25%