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Abstract
Purpose: The human retinal vasculature has been demonstrated to exhibit fractal, or statistically self similar properties. Fractal analysis offers a simple quantitative method to characterise the complexity of the branching vessel network in the retina. Several methods have been proposed to quantify the fractal properties of the retina.
Methods: Twenty five healthy volunteers underwent retinal photography, retinal oximetry and ocular biometry. A robust method to evaluate the fractal properties of the retinal vessels is proposed; it consists of manual vessel segmentation and box counting of 50 degree retinal photographs centred on the fovea.
Results: Data is presented on the associations between the fractal properties of the retinal vessels and various functional properties of the retina.
Conclusion Fractal properties of the retina could offer a promising tool to assess the risk and prognostic factors that define retinal disease. Outstanding efforts surround the need to adopt a standardised protocol for assessing the fractal properties of the retina, and further demonstrate its association with disease processes.
Methods: Twenty five healthy volunteers underwent retinal photography, retinal oximetry and ocular biometry. A robust method to evaluate the fractal properties of the retinal vessels is proposed; it consists of manual vessel segmentation and box counting of 50 degree retinal photographs centred on the fovea.
Results: Data is presented on the associations between the fractal properties of the retinal vessels and various functional properties of the retina.
Conclusion Fractal properties of the retina could offer a promising tool to assess the risk and prognostic factors that define retinal disease. Outstanding efforts surround the need to adopt a standardised protocol for assessing the fractal properties of the retina, and further demonstrate its association with disease processes.
| Original language | English |
|---|---|
| Article number | T014 |
| Journal | Acta Ophthalmologica |
| Volume | 91 |
| Issue number | Suppl.s252 |
| DOIs | |
| Publication status | Published - 6 Aug 2013 |
| Event | European Association for Vision and Eye Research conference 2013 - Nice, France Duration: 18 Sept 2013 → 21 Sept 2013 |
Bibliographical note
2013 European Association for Vision and Eye Research Conference, 18-21 September 2013, Nice, France.Fingerprint
Dive into the research topics of 'The fractal properties of the retinal vascular architecture'. Together they form a unique fingerprint.Research output
- 2 Conference abstract
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Multispectral retinal image analysis (MRIA) for the assessment of subretinal fibrosis in neovascular age-related macular degeneration (nAMD)
Calcagni, A., Styles, I. B., Palmer, A. D., Shen, Y., Bartlett, H., Eperjesi, F., Gibson, J. M. & Claridge, E., 6 Aug 2013, In: Acta Ophthalmologica. 91, Suppl.s252, F046.Research output: Contribution to journal › Conference abstract › peer-review
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Retinal arteriolar diameter response to flicker light provocation - A useful marker for risk stratification in cardiovascular disease?
Heitmar, R., Blann, A. & Summers, A. J., 6 Aug 2013, In: Acta Ophthalmologica. 91, Suppl.s252, F059.Research output: Contribution to journal › Conference abstract › peer-review