The influence of aluminium, administered in the diet and in drinking water, on biopterin metabolism

Richard A. Armstrong, J. Anderson, Jim D. Cowburn, Juliette Cox, J.A. Blair

Research output: Unpublished contribution to conferenceUnpublished Conference Paperpeer-review

Abstract

To investigate the neurotoxic effects of aluminium (Al) three studies were carried out in which Al was administered: 1) in the diet, 2) as a suspension of aluminium acetate in drinking water and 3) a long-term study in which aluminosilicates were incorporated into a pelleted diet. Admistration of Al in the drinking water significantly reduced total brain biopterin. However, no significant affect of Al in the diet on total bipterins or BH4 synthesis was found.
Original languageEnglish
Publication statusUnpublished - 1992
Event11th Winter Workshop on Pteridines - St. Christoph, Arlberg (AT)
Duration: 15 Feb 199222 Feb 1992

Workshop

Workshop11th Winter Workshop on Pteridines
CitySt. Christoph, Arlberg (AT)
Period15/02/9222/02/92

Bibliographical note

Abstract appearing in Biol Chem, 373:P986

Keywords

  • neurotoxic effects
  • aluminium
  • brain

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