The use of atomic force microscopy in investigating particle caking mechanisms

M.C. Leaper*, D.C. Prime

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Spray-dried materials are being used increasingly in industries such as food, detergent and pharmaceutical manufacture. Spray-dried sodium carbonate is an important product that has a great propensity to cake; its moisture-sorption properties are very different to the crystalline and amorphous species, with a great affinity for atmospheric moisture. This work demonstrates how the noncontact surface analysis of individual particles using atomic force microscopy can highlight the possible mechanisms of unwanted agglomeration. The nondestructive nature of this method allows cycling of localised humidity in situ and repeated scanning of the same particle area. The resulting topography and phase scans showed that humidity cycling caused changes in the distribution of material phases that were not solely dependent on topographical changes.

Original languageEnglish
Pages (from-to)1801-1805
Number of pages5
JournalChemical Engineering and Technology
Issue number10
Publication statusPublished - Oct 2013

Bibliographical note

Funding: UK EPSRC [EP/GO/016224/1]


  • atomic force microscopy
  • caking
  • moisture sorption


Dive into the research topics of 'The use of atomic force microscopy in investigating particle caking mechanisms'. Together they form a unique fingerprint.

Cite this