Towards novel compact laser sources for non-invasive diagnostics and treatment

Edik U. Rafailov; Karina S. Litvinova; Sergei G. Sokolovski

doi:10.1117/12.2193777

Towards novel compact laser sources for non-invasive diagnostics and treatment

Edik U. Rafailov, Karina S. Litvinova, Sergei G. Sokolovski

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

An important field of application of lasers is biomedical optics. Here, they offer great utility for diagnosis, therapy and surgery. For the development of novel methods of laser-based biomedical diagnostics careful study of light propagation in biological tissues is necessary to enhance our understanding of the optical measurements undertaken, increase research and development capacity and the diagnostic reliability of optical technologies. Ultimately, fulfilling these requirements will increase uptake in clinical applications of laser based diagnostics and therapeutics. To address these challenges informative biomarkers relevant to the biological and physiological function or disease state of the organism must be selected. These indicators are the results of the analysis of tissues and cells, such as blood. For non-invasive diagnostics peripheral blood, cells and tissue can potentially provide comprehensive information on the condition of the human organism. A detailed study of the light scattering and absorption characteristics can quickly detect physiological and morphological changes in the cells due to thermal, chemical, antibiotic treatments, etc [1-5]. The selection of a laser source to study the structure of biological particles also benefits from the fact that gross pathological changes are not induced and diagnostics make effective use of the monochromatic directional coherence properties of laser radiation.

Original language	English
Title of host publication	Biosensing and Nanomedicine VIII
Editors	Hooman Mohseni, Massoud H. Agahi, Manijeh Razeghi
Publisher	SPIE
Number of pages	12
ISBN (Print)	9781628417166
DOIs	https://doi.org/10.1117/12.2193777
Publication status	Published - 21 Aug 2015
Event	Biosensing and nanomedicine VIII - San Diego, United States Duration: 9 Aug 2015 → 12 Aug 2015

Publication series

Name	SPIE proceedings
Publisher	SPIE
Volume	9550
ISSN (Print)	0277-786X

Conference

Conference	Biosensing and nanomedicine VIII
Country/Territory	United States
City	San Diego
Period	9/08/15 → 12/08/15

Bibliographical note

Edik U. Rafailov ; Karina S. Litvinova and Sergei G. Sokolovski, "Towards novel compact laser sources for non-invasive diagnostics and treatment", Proc. SPIE 9550, Biosensing and Nanomedicine VIII, 95500G (August 21, 2015)

Copyright 2015. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

DOI: http://dx.doi.org/10.1117/12.2193777

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10.1117/12.2193777

Novel compact laser sources for non-invasive diagnostics and treatment
Edik U. Rafailov ; Karina S. Litvinova and Sergei G. Sokolovski, "Towards novel compact laser sources for non-invasive diagnostics and treatment", Proc. SPIE 9550, Biosensing and Nanomedicine VIII, 95500G (August 21, 2015) Copyright 2015. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2193777
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http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=2430914

Cite this

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title = "Towards novel compact laser sources for non-invasive diagnostics and treatment",

abstract = "An important field of application of lasers is biomedical optics. Here, they offer great utility for diagnosis, therapy and surgery. For the development of novel methods of laser-based biomedical diagnostics careful study of light propagation in biological tissues is necessary to enhance our understanding of the optical measurements undertaken, increase research and development capacity and the diagnostic reliability of optical technologies. Ultimately, fulfilling these requirements will increase uptake in clinical applications of laser based diagnostics and therapeutics. To address these challenges informative biomarkers relevant to the biological and physiological function or disease state of the organism must be selected. These indicators are the results of the analysis of tissues and cells, such as blood. For non-invasive diagnostics peripheral blood, cells and tissue can potentially provide comprehensive information on the condition of the human organism. A detailed study of the light scattering and absorption characteristics can quickly detect physiological and morphological changes in the cells due to thermal, chemical, antibiotic treatments, etc [1-5]. The selection of a laser source to study the structure of biological particles also benefits from the fact that gross pathological changes are not induced and diagnostics make effective use of the monochromatic directional coherence properties of laser radiation.",

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Towards novel compact laser sources for non-invasive diagnostics and treatment. / Rafailov, Edik U.; Litvinova, Karina S.; Sokolovski, Sergei G.
Biosensing and Nanomedicine VIII. ed. / Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi. SPIE, 2015. 95500G (SPIE proceedings; Vol. 9550).

Research output: Chapter in Book/Published conference output › Conference publication

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ER -

Towards novel compact laser sources for non-invasive diagnostics and treatment

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