Use of fluorescent optical fibre probe for recording parameters of brain metabolism in rat model

Alexander Alekseyev, Evgeniya Seryogina, Olga Stelmashchuk, Evgeny A. Zherebtsov, Gennadii Piavchenko, Evgeny Vorobyev, Elena Kuznetsova, Edik U. Rafailov, Alyona Kuznetsova, Andrey Dunaev, Ilya Rafailov, Jürgen Popp (Editor), Valery V. Tuchin, Francesco S. Pavone (Editor)

Research output: Chapter in Book/Published conference outputConference publication

Abstract

This studiy was carried out on groups of clinically healthy male Wistar rats. Animals received distilled drinking water ad libitum for 1 month, water containing succinic acid, water containing zinc sulphate and succinate zinc. Using the method of fluorescence spectroscopy, the parameters of brain metabolism in vivo in a model of laboratory rats was investigated. Based on data obtained by fluorescence spectroscopy, we have registered a change in the degree of cellular respiration in different structures of the cerebral cortex with the toxic effect of zinc compounds and succinic acid on the oxygen exchange process.
Original languageEnglish
Title of host publicationProceedings of SPIE
Subtitle of host publicationBiophotonics: Photonic Solutions for Better Health Care VI
PublisherSPIE
Number of pages6
Volume10685
DOIs
Publication statusPublished - 17 May 2018
EventBiophotonics: Photonic Solutions for Better Health Care - Strasbourg, France
Duration: 22 Apr 201826 Apr 2018

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume10685
ISSN (Print)0277-786X

Conference

ConferenceBiophotonics: Photonic Solutions for Better Health Care
Period22/04/1826/04/18

Bibliographical note

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